Determinants of heterogeneous adherence to HIV-antiretroviral therapies in the multicenter AIDS cohort study
Determinants of heterogeneous adherence to HIV-antiretroviral therapies in the multicenter AIDS cohort study
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DOI：
10.1097/00126334-200101010-00012
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发表时间：
2001-01-01
期刊：
影响因子：
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通讯作者：
Jacobson, LP
中科院分区：
文献类型：
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作者：
Kleeberger, CA;Phair, JP;Jacobson, LP
需要对 HIV 抗逆转录病毒治疗 (ART) 的依从性进行评估，以研究治疗效果并确定需要重点教育的亚组。该研究的目标是使用一天内自我报告的回忆来描述 ART 依从性水平，并描述较低依从性的决定因素。还研究了依从性和药物假期之间对 HIV RNA 水平的相互作用。自我报告的完美依从性被定义为服用当前艾滋病毒药物规定的所有剂量和数量的药丸。独立预测因子
Assessment of adherence to HIV antiretroviral therapy (ART) is required for studying therapeutic effectiveness and identifying subgroups needing focused education. The study's goals were to describe the level of ART adherence using self-reported recall over a it-day period and to characterize determinants of lower adherence. The interaction between adherence and drug holidays on level of HIV RNA also was investigated. Perfect self-reported adherence was defined as taking all doses and numbers of pills as prescribed for current HIV medications. Independent predictors of