Biodegradation assessment of nanostructured fluoridated hydroxyapatite coatings on biomedical grade magnesium alloy
Biodegradation assessment of nanostructured fluoridated hydroxyapatite coatings on biomedical grade magnesium alloy
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DOI：
10.1016/j.ceramint.2014.06.129
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发表时间：
2014-11
影响因子：
5.2
通讯作者：
Ramin Rojaee;M. Fathi;K. Raeissi;A. Sharifnabi
中科院分区：
文献类型：
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作者：
Ramin Rojaee;M. Fathi;K. Raeissi;A. Sharifnabi
与管理镁降解速率相关的挑战需要新技术来确保其生物安全性和可靠性。采用电泳沉积法在微弧氧化AZ91镁合金表面包覆不同氟化程度的纳米羟基磷灰石粉体。采用Zeta电位和电导率监测技术为涂层提供合适的条件。在模拟体液溶液浸泡过程中的生物腐蚀过程和相关的矿化进行了解释。基于这些结果，提出了在微弧处理的AZ91种植体上的25%氟取代羟基磷灰石涂层以轻微的侵入行为刺激骨长入，并且在其寿命期间没有术后并发症。
The challenges associated with managing Mg degradation rate demand novel technologies to ensure its biological safety and reliability. Here, fluoridated hydroxyapatite nanopowders with different degrees of fluoridation were coated on microarc oxidized AZ91 magnesium alloy via the electrophoretic deposition method. Zeta potential and conductivity monitoring techniques were employed to offer appropriate conditions for the coatings. The bio-corrosion process and the associated mineralization were interpreted during the immersion in simulated body fluid solution. Based on the results, the 25% fluorine substituted hydroxyapatite coating on microarc-treated AZ91 implant was proposed to stimulate bone ingrowth in a minor invasive behavior and without post-operative complications during its lifespan.