Association of IgA nephropathy and myasthenia gravis.

Association of IgA nephropathy and myasthenia gravis.
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IgA 肾病与重症肌无力的关联。

DOI:
10.1159/000185331
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发表时间:
1989
期刊:
影响因子:
2.5
通讯作者:
H. Sakai
H. Sakai
中科院分区:
医学4区
文献类型:
--
作者:
M. Miyazaki;N. Kimura;K. Imai;K. Eguchi;M. Yagame;M. Miura;M. Endoh;Y. Tomino;Y. Nomoto;H. Sakai

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三例伊加肾病与重症肌无力的描述。在所有3例病例中,重症肌无力均在发现肾小球肾炎后出现。2例患者胸腺切除后肌无力症状改善,但肾脏疾病进展未改善。在这两种疾病中观察到一些全身异常,包括免疫学畸变。据推测,T细胞异常伊加肾病可能是独立的重症肌无力的发展。
Three patients with IgA nephropathy associated with myasthenia gravis are described. In all 3 cases, myasthenia gravis emerged after the discovery of glomerulonephritis. Myasthenic symptoms were improved by thymectomy in 2 cases, but progression of the renal disease was not improved. Some systemic abnormalities, including immunological aberrations, were observed in these two disorders. It is postulated that T cell abnormalities in IgA nephropathy might be independent of the development of myasthenia gravis.