Rapid Improvement of thyroid storm-related hemodynamic collapse by aggressive anti-thyroid therapy including steroid pulse: A case report.
Rapid Improvement of thyroid storm-related hemodynamic collapse by aggressive anti-thyroid therapy including steroid pulse: A case report.
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DOI：
10.1097/md.0000000000007053
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发表时间：
2017-06
期刊：
影响因子：
1.6
通讯作者：
Komuro I
中科院分区：
文献类型：
--
作者：
Kiriyama H;Amiya E;Hatano M;Hosoya Y;Maki H;Nitta D;Saito A;Shiraishi Y;Minatsuki S;Sato T;Murakami H;Uehara M;Manaka K;Makita N;Watanabe M;Komuro I
心力衰竭在甲状腺功能亢进症患者中相对常见，但甲状腺毒性心肌病伴左心室（LV）收缩功能差则非常罕见。我们经历了一例代表性病例，患者出现与甲状腺风暴相关的重度LV功能障碍，暂时需要体外膜肺氧合（ECMO）。甲状腺毒性心肌病。积极的抗甲状腺治疗，包括类固醇脉冲甲状腺功能亢进症，导致心脏功能的显着改善，她成功地脱离ECMO。本病例最突出的特点是通过加强抗甲状腺治疗，包括类固醇脉冲，在甲状腺激素水平未恢复正常的情况下，心脏损伤迅速减少，心功能改善。在甲状腺危象中，各种全身炎症反应有不同的时程，其中以心脏表型的出现最为显著和关键。
Heart failure is relatively common in patients with hyperthyroidism, but thyrotoxic cardiomyopathy with poor left ventricular (LV) systolic function is very rare. We experienced a representative case of a patient who presented with severe LV dysfunction related to thyroid storm and needed extracorporeal membrane oxygenation (ECMO) temporally. Thyrotoxic cardiomyopathy. Aggressive antithyroid therapy, including steroid pulse to hyperthyroidism, leads to the dramatic improvement of cardiac function and she was successfully weaned from ECMO. The most outstanding feature of the current case was the rapid decrease of cardiac injury and improvement of cardiac function by strengthening antithyroid therapy, including steroid pulse, without thyroid hormone level normalization. In thyroid storm, various systemic inflammatory reactions have different time courses and among them, the cardiac phenotype emerges in most striking and critical ways.