Thoracic and Abdominal Lymphatic Pump Techniques Inhibit the Growth of S. pneumoniae Bacteria in the Lungs of Rats
Thoracic and Abdominal Lymphatic Pump Techniques Inhibit the Growth of S. pneumoniae Bacteria in the Lungs of Rats
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DOI：
10.1089/lrb.2013.0007
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发表时间：
2013-09-01
影响因子：
1.4
通讯作者：
Hodge, Lisa M.
中科院分区：
文献类型：
--
作者：
Creasy, Caitlin;Schander, Artur;Hodge, Lisa M.
背景：整骨医生利用称为淋巴泵技术 (LPT) 的手工医学技术来改善淋巴流动并增强免疫力。临床研究表明，LPT可增强细菌疫苗的抗体反应，缩短呼吸道疾病患者的咳嗽持续时间，缩短肺炎患者的静脉抗生素治疗和住院时间。本研究的目的是确定胸部 LPT (Th-LPT) 或腹部 LPT (Ab-LPT) 是否会减少急性肺炎大鼠肺部的肺炎链球菌菌落形成单位 (CFU)。方法和结果：大鼠鼻腔感染肺炎链球菌，并接受对照、假手术、Ab-LPT 或 Th-LPT，每天一次，连续 3 天。感染后第4天，取出肺部并对细菌进行计数。每日 3 次应用 Ab-LPT 或 Th-LPT 能够显着 (p
Background: Osteopathic physicians utilize manual medicine techniques called lymphatic pump techniques (LPT) to improve lymphatic flow and enhance immunity. Clinical studies report that LPT enhances antibody responses to bacterial vaccines, shortens duration of cough in patients with respiratory disease, and shortens the duration of intravenous antibiotic therapy and hospital stay in patients with pneumonia. The purpose of this study was to identify if thoracic LPT (Th-LPT) or abdominal LPT (Ab-LPT) would reduce Streptococcus pneumoniae colony-forming units (CFU) in the lungs of rats with acute pneumonia. Methods and Results: Rats were nasally infected with S. pneumoniae and received either control, sham, Ab-LPT, or Th-LPT once daily for 3 consecutive days. On day 4 post-infection, lungs were removed and bacteria were enumerated. Three daily applications of either Ab-LPT or Th-LPT were able to significantly (p