ZnO/CNTs nanocomposite/ionic liquid carbon paste electrode for determination of noradrenaline in human samples
ZnO/CNTs nanocomposite/ionic liquid carbon paste electrode for determination of noradrenaline in human samples
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DOI：
10.1016/j.electacta.2014.01.006
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发表时间：
2014-03
影响因子：
6.6
通讯作者：
A. Pahlavan;V. Gupta;Afsaneh L. Sanati;F. Karimi;Mehdi Yoosefian;Mojtaba Ghadami
中科院分区：
文献类型：
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作者：
A. Pahlavan;V. Gupta;Afsaneh L. Sanati;F. Karimi;Mehdi Yoosefian;Mojtaba Ghadami
在本研究中，我们描述了新型纳米复合材料（ZnO/CNT）室温离子液体（RTIL）改性碳糊电极的合成和应用，作为伏安传感器用于测定药物和生物样品中的去甲肾上腺素（NE）。所提出的传感器对水溶液中 NE 的电氧化表现出增强的有效性。离子液体（1, 3-二丙基咪唑溴化物）ZnO/CNTs 碳糊电极（ZnO/CNTs/IL/CPE）表面的 NE 氧化峰电位出现在 440 mV。方波伏安法 (SWV) 作为一种非常灵敏的电化学方法用于测定 NE。线性响应范围和检测限分别为 5.0 × 10−8 至 4.5 × 10−4M 和 2.0 × 10−8M。该传感器已成功应用于运动员尿液和安瓿样品中 NE 的测定。
In the presence study we describe synthesis and application of new nanocomposite (ZnO/CNTs) room temperature ionic liquid (RTIL) modified carbon paste electrode as a voltammetric sensor for determination of noradrenaline (NE) in pharmaceutical and biological samples. The proposed sensor exhibits an enhanced effectiveness for the electro-oxidation of NE in aqueous solution. The oxidation peak potential for NE at a surface of the ionic liquid (1, 3-dipropylimidazolium bromide) ZnO/CNTs carbon paste electrode (ZnO/CNTs/IL/CPE) appeared at 440 mV. Square wave voltammetry (SWV) was applied as a very sensitive electrochemical method for the determination of NE. The linear response range and detection limit were found to be 5.0 × 10−8to 4.5 × 10−4M and 2.0 × 10−8M, respectively. The proposed sensor was successfully applied for the determination of NE in urine athletes and ampoule samples.