Evaluation of economic costs of a measles outbreak and outbreak response activities in Keffa Zone, Ethiopia
Evaluation of economic costs of a measles outbreak and outbreak response activities in Keffa Zone, Ethiopia
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DOI：
10.1016/j.vaccine.2014.06.035
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发表时间：
2014-07-31
期刊：
影响因子：
5.5
通讯作者：
Vijayaraghavan, Maya
中科院分区：
文献类型：
--
作者：
Wallace, Aaron S.;Masresha, Balcha G.;Vijayaraghavan, Maya
目的：利用卫生部门和家庭的角度，评估2011年10月1日埃塞俄比亚凯法地区发生的麻疹暴发和应对活动的经济影响。2012年4月8日，埃塞俄比亚凯法地区报告了5257例麻疹病例。方法：我们通过对政府和合作机构工作人员的访谈和记录审查，以及对100例麻疹病例患者及其照顾者的调查，收集成本投入数据。我们使用成本投入数据来估计以下暴发和应对活动的财务和机会成本：调查、治疗、病例管理、积极监测、免疫运动和加强免疫系统。结果：暴发和应对的经济成本为758,869美元(美元)，包括327,545美元(62.31美元/病例)的机会成本和431,324美元(82.05美元/病例)的财务成本。卫生部门费用，包括免疫运动(72.29美元/病例)，占经济成本的80%。家庭经济成本为29.18美元/箱，相当于家庭年收入中位数的6%。92%的财务成本由伙伴机构承担。结论：与家庭收入和卫生部门支出相比，麻疹暴发的经济成本是巨大的。将两剂麻疹疫苗接种率提高到95%以上，既能降低麻疹发病率，又能为卫生部门和家庭节省大量与疫情有关的费用。爱思唯尔有限公司出版。
Objective: To estimate the economic impact of a measles outbreak and response activities that occurred in Keffa Zone, Ethiopia with 5257 reported cases during October 1, 2011 April 8, 2012, using the health sector and household perspectives.Methods: We collected cost input data through interviews and record reviews with government and partner agency staff and through a survey of 100 measles cases-patients and their caretakers. We used cost input data to estimate the financial and opportunity costs of the following outbreak and response activities: investigation, treatment, case management, active surveillance, immunization campaigns, and immunization system strengthening.Findings: The economic cost of the outbreak and response was 758,869 United States dollars (US$), including the opportunity cost of US$327,545 (US$62.31/case) and financial cost of US$431,324 (US$82.05/case). Health sector costs, including the immunization campaign (US$72.29/case), accounted for 80% of the economic cost. Household economic cost was US$29.18/case, equal to 6% of the household median annual income. 92% of financial costs were covered by partner agencies.Conclusion: The economic cost of the measles outbreak was substantial when compared to household income and health sector expenditures. Improvement in two-dose measles vaccination coverage above 95% would both reduce measles incidence and save considerable outbreak-associated costs to both the health sector and households. Published by Elsevier Ltd.