Liver transplantation for combined hepatocellular cholangiocarcinoma
Liver transplantation for combined hepatocellular cholangiocarcinoma
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DOI：
10.1016/s1015-9584(09)60149-4
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发表时间：
2007-04-01
影响因子：
3.5
通讯作者：
Fan, Sheung Tat
中科院分区：
文献类型：
--
作者：
Chan, Albert Chi-Yan;Lo, Chung Mau;Fan, Sheung Tat
合并肝细胞胆管癌（cHCC-CC）是原发性肝癌中一种罕见的组织学变异。这种合并型病变具有侵袭性临床病程，预后不良。虽然原位肝移植在肝细胞癌治疗中的作用是明确的，但迄今为止，还没有关于原位肝移植在cHCC-CC中的治疗价值的报道。我们报告我们对3例cHCC-CC患者进行原位肝移植的经验。1例患者在肝移植后16.5个月死于远处转移，而另外2例患者在移植后分别存活了35个月和25个月。
Combined hepatocellular cholangiocarcinoma (cHCC-CC) is an uncommon histological variant of primary liver cancer. This combined type of turnout lesion follows an aggressive clinical course with an unfavourable prognosis. Although the role of orthotopic liver transplantation in the management for hepatocellular carcinoma is well defined, to date, there has been no report on its treatment value for cHCC-CC. We report our experience of orthotopic liver transplantation in three patients with cHCC-CC. One patient succumbed to distant metastases 16.5 months after liver transplantation whereas the other two patients continued to survive 35 and 25 months after transplantation, respectively.