Inter-station intensity standardization for whole-body MR data
Inter-station intensity standardization for whole-body MR data
复制标题
DOI：
10.1002/mrm.26098
复制
发表时间：
2017-01-01
影响因子：
3.3
通讯作者：
van der Geest, Rob J.
中科院分区：
文献类型：
--
作者：
Dzyubachyk, Oleh;Staring, Marius;van der Geest, Rob J.
PurposeTo开发和验证一种方法进行站间强度标准化的多光谱全身MR data.MethodsDifferent方法映射到参考强度空间的每个采集的图像堆栈的强度进行了开发和验证。注册策略包括：直接注册到参考站（策略1），渐进注册到相邻站没有（策略2），和（策略3）使用来自相邻站的重叠区域的信息。对于策略3，提出并验证了两个正则化修改。所有方法均在两个多光谱全身MR数据集上进行测试：多发性骨髓瘤患者数据集（48例受试者）和全身MR血管造影数据集（33例受试者）。
PurposeTo develop and validate a method for performing inter-station intensity standardization in multispectral whole-body MR data.MethodsDifferent approaches for mapping the intensity of each acquired image stack into the reference intensity space were developed and validated. The registration strategies included: direct registration to the reference station (Strategy 1), progressive registration to the neighboring stations without (Strategy 2), and with (Strategy 3) using information from the overlap regions of the neighboring stations. For Strategy 3, two regularized modifications were proposed and validated. All methods were tested on two multispectral whole-body MR data sets: a multiple myeloma patients data set (48 subjects) and a whole-body MR angiography data set (33 subjects).ResultsFor both data sets, all strategies showed significant improvement of intensity homogeneity with respect to vast majority of the validation measures (P