Longitudinal relationships between family routines and biological profiles among youth with asthma.

Longitudinal relationships between family routines and biological profiles among youth with asthma.
复制标题

哮喘青少年的家庭日常生活与生物学特征之间的纵向关系。

DOI:
10.1037/a0018311
复制
发表时间:
2010
期刊:
Health psychology : official journal of the Division of Health Psychology, American Psychological Association
影响因子:
--
通讯作者:
Chen,Edith
Chen,Edith
中科院分区:
--
文献类型:
--
作者:
Schreier,HannahMC;Chen,Edith

文献摘要

参考文献

相似文献

目的探讨哮喘青少年哮喘炎症标志物的纵向轨迹是否可以通过家庭常规水平来预测。在18个月的研究期间,通过父母问卷和每6个月采集的青少年外周血样本来评估DesignFamily常规。使用分层线性模型评估纵向关系。主要观察指标:丝裂原刺激哮喘相关细胞因子的产生,特别是IL-4、IL-5和IL-13。结果在整个研究过程中,家庭环境中有更多家庭常规的青少年IL-13(但IL-4或IL-5)下降。反过来,人体内分析表明,当刺激IL-13的产生高时,哮喘症状也高,这表明IL-13随时间变化的临床相关性。各种各样的儿童和父母的社会心理以及儿童的行为特征都不能解释这些影响。然而,药物的使用消除了家庭惯例和刺激IL-13产生之间的关系。结论我们的研究表明,家庭常规在生物学水平上预测哮喘结局,可能通过影响药物使用。在治疗哮喘时考虑日常家庭行为可能有助于改善青少年哮喘患者的生物学和临床特征。(PsycInfo数据库记录(c) 2022 APA,版权所有)
ObjectiveTo investigate whether longitudinal trajectories of inflammatory markers of asthma can be predicted by levels of family routines in youth with asthma.DesignFamily routines were assessed through parent questionnaires and peripheral blood samples obtained from youth every 6 months throughout the 18-month study period. Longitudinal relationships were evaluated using hierarchical linear modeling.Main Outcome MeasuresMitogen-stimulated production of cytokines implicated in asthma, specifically IL-4, IL-5, and IL-13.ResultsYouth with more family routines in their home environment showed decreases in IL-13 (but not IL-4 or IL-5) over the course of the study period. In turn, within-person analyses indicated that at times when stimulated production of IL-13 was high, asthma symptoms were also high, pointing to the clinical relevance of changes in IL-13 over time. A variety of child and parent psychosocial as well as child behavioral characteristics could not explain these effects. However, medication use eliminated the relationship between family routines and stimulated production of IL-13.ConclusionOur study suggests that family routines predict asthma outcomes at the biological level, possibly through influencing medication use. Considering daily family behaviors when treating asthma may help improve both biological and clinical profiles in youth with asthma.(PsycInfo Database Record (c) 2022 APA, all rights reserved)
NIDA 成瘾研究中心的进度报告,马里兰州巴尔的摩,1982 年。
DOI: --
发表时间: 1983
期刊: NIDA research monograph
影响因子: --
作者:
Jasinski Dr;J. Re;Hickey Je;C. Haertzen;J. Henningfield;K. Kumor
通讯作者: K. Kumor
DOI: --
发表时间: 1970
期刊: Chest
影响因子: 9.6
作者:
David M. Spain;V. A. Bradess
通讯作者: V. A. Bradess
DOI: --
发表时间: 1983
期刊: The Journal of pharmacology and experimental therapeutics
影响因子: --
作者:
Goldberg,SR;Spealman,RD
通讯作者: Spealman,RD
大鼠慢性静脉插管。
DOI: 10.1152/jappl.1964.19.3.540
发表时间: 1964
影响因子: 3.3
作者:
J. Weeks;J. D. Davis
通讯作者: J. D. Davis
吸烟:对高尼古丁烟碱的依赖。
DOI: 10.3109/03602537808993776
发表时间: 1978
影响因子: 5.9
作者:
M. Russell;Colin Feyerabend
通讯作者: Colin Feyerabend