Longitudinal relationships between family routines and biological profiles among youth with asthma.
Longitudinal relationships between family routines and biological profiles among youth with asthma.
复制标题
哮喘青少年的家庭日常生活与生物学特征之间的纵向关系。
DOI:
10.1037/a0018311
复制
发表时间:
2010
期刊:
影响因子:
--
通讯作者:
Chen,Edith
中科院分区:
文献类型:
--
作者:
Schreier,HannahMC;Chen,Edith
ObjectiveTo investigate whether longitudinal trajectories of inflammatory markers of asthma can be predicted by levels of family routines in youth with asthma.DesignFamily routines were assessed through parent questionnaires and peripheral blood samples obtained from youth every 6 months throughout the 18-month study period. Longitudinal relationships were evaluated using hierarchical linear modeling.Main Outcome MeasuresMitogen-stimulated production of cytokines implicated in asthma, specifically IL-4, IL-5, and IL-13.ResultsYouth with more family routines in their home environment showed decreases in IL-13 (but not IL-4 or IL-5) over the course of the study period. In turn, within-person analyses indicated that at times when stimulated production of IL-13 was high, asthma symptoms were also high, pointing to the clinical relevance of changes in IL-13 over time. A variety of child and parent psychosocial as well as child behavioral characteristics could not explain these effects. However, medication use eliminated the relationship between family routines and stimulated production of IL-13.ConclusionOur study suggests that family routines predict asthma outcomes at the biological level, possibly through influencing medication use. Considering daily family behaviors when treating asthma may help improve both biological and clinical profiles in youth with asthma.(PsycInfo Database Record (c) 2022 APA, all rights reserved)
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DOI:
--
发表时间:
1983
期刊:
NIDA research monograph
影响因子:
--
作者:
Jasinski Dr;J. Re;Hickey Je;C. Haertzen;J. Henningfield;K. Kumor
通讯作者:
K. Kumor
影响因子:
9.6
作者:
David M. Spain;V. A. Bradess
通讯作者:
V. A. Bradess
DOI:
--
发表时间:
1983
期刊:
The Journal of pharmacology and experimental therapeutics
影响因子:
--
作者:
Goldberg,SR;Spealman,RD
通讯作者:
Spealman,RD
影响因子:
3.3
作者:
J. Weeks;J. D. Davis
通讯作者:
J. D. Davis
影响因子:
5.9
作者:
M. Russell;Colin Feyerabend
通讯作者:
Colin Feyerabend