Oxidation of phenylpyruvic acid.
Oxidation of phenylpyruvic acid.
复制标题
苯丙酮酸的氧化。
DOI：
10.1016/0304-4165(87)90207-8
复制
发表时间：
1987
期刊：
影响因子：
--
通讯作者：
G. Cilento
中科院分区：
文献类型：
--
作者：
M. Villablanca;G. Cilento
Mn ~（2+）催化苯丙氨酸的好氧氧化。苯甲醛和草酸盐是主要的产品，前者在一定程度上产生的激发态，如叶绿素敏化发射。通过添加辣根过氧化物酶，氧消耗和排放都得到增强。在酶的存在下，含卤素的咕吨染料也敏化发射。从苯甲醛/草酸盐产物比率的值，可以推断，两个氧化途径是有效的。其中一个过程通过二氧杂环丁烷中间体进行，并负责激发苯甲醛;另一个过程涉及α-酮-β-过氧化氢内酯，不产生草酸盐。该酶似乎有利于二氧杂环丁烷途径。这些路线在生物系统中的相对重要性进行了讨论。
Mn2+catalyzes the aerobic oxidation of phenylpyruvic acid. Benzaldehyde and oxalate are the major products, the former being generated to some extent in an excited state, as indicated by chlorophyll-sensitized emission. Both oxygen consumption and emission are enhanced by addition of horseradish peroxidase. In the presence of the enzyme, halogen-containing xanthene dyes also sensitize the emission. From the values of the benzaldehyde/oxalate product ratio, it is inferred that two oxidation pathways are operative. One of these proceeds via a dioxetane intermediate and is responsible for the excited benzaldehyde; the other, which involves an α-keto-β-peroxylactone, does not produce oxalate. The enzyme appears to favour the dioxetane route. The relative importance of these routes in biological systems is discussed.
大肠杆菌中正常代谢物引起的诱变：苯丙氨酸诱变依赖于容易出错的 DNA 修复。
DOI：
10.1016/0027-5107(86)90002-3
发表时间：
1986
期刊：
Mutation research
影响因子：
--
作者：
Sargentini,NJ;Smith,KC
通讯作者：
Smith,KC