Traces of early Eurasians in the Mansi of northwest Siberia revealed by mitochondrial DNA analysis
Traces of early Eurasians in the Mansi of northwest Siberia revealed by mitochondrial DNA analysis
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DOI：
10.1086/339524
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发表时间：
2002-04-01
影响因子：
9.8
通讯作者：
Sukernik, RI
中科院分区：
文献类型：
--
作者：
Derbeneva, OA;Starikovskaya, EB;Sukernik, RI
通过限制性片段长度多态性分析、控制区测序和编码区其他信息位点的测序，对 98 Mansi 的线粒体 DNA (mtDNA) 进行了序列变异分析。尽管在曼西人中检测到的 mtDNA 中有 63.3% 属于欧亚西部谱系（例如单倍群 UK、TJ 和 HV），但其余 36.7% 包含东部欧亚谱系的子集（例如单倍群 A、C、D、F、G 和 M）。在欧亚西部谱系中，亚单倍群 U4 以及谱系 U5、U7 和 J2 的出现频率高达 16.3%。这表明居住在乌拉尔山脉以东的原住民可能包括来自中东/东南欧的旧石器时代晚期早期扩张的残余物。曼西人中东欧亚线粒体DNA谱系的增加引入了一种可能性，即原始欧亚人包含一系列大型单倍群M和N谱系，这些谱系随后在地理上分布，并且旧石器时代的扩张可能在分裂为西方和东方人类群体之前就已经到达了西伯利亚的这一地区。
The mitochondrial DNA (mtDNA) of 98 Mansi, an ancient group (formerly known as "Vogul") of Uralic-speaking fishers and hunters on the eastern slope of the northern Ural Mountains, were analyzed for sequence variants by restriction fragment-length polymorphism analysis, control-region sequencing, and sequencing of additional informative sites in the coding region. Although 63.3% of the mtDNA detected in the Mansi falls into western Eurasian lineages (e. g., haplogroups UK, TJ, and HV), the remaining 36.7% encompass a subset of eastern Eurasian lineages (e. g., haplogroups A, C, D, F, G, and M). Among the western Eurasian lineages, subhaplogroup U4 was found at a remarkable frequency of 16.3%, along with lineages U5, U7, and J2. This suggests that the aboriginal populations residing immediately to the east of the Ural Mountains may encompass remnants of the early Upper Paleolithic expansion from the Middle East/southeastern Europe. The added presence of eastern Eurasian mtDNA lineages in the Mansi introduces the possibilities that proto-Eurasians encompassed a range of macrohaplogroup M and N lineages that subsequently became geographically distributed and that the Paleolithic expansion may have reached this part of Siberia before it split into western and eastern human groups.