Do People Who Develop AIDS within 12 Months of HIV Diagnosis Delay HIV Testing?
Do People Who Develop AIDS within 12 Months of HIV Diagnosis Delay HIV Testing?
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DOI：
10.1177/003335491112600411
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发表时间：
2011-07-01
影响因子：
3.3
通讯作者：
Dilley, James
中科院分区：
文献类型：
--
作者：
Schwarcz, Sandra K.;Hsu, Ling;Dilley, James
客观的。在 HIV 诊断后 12 个月内被诊断出患有 AIDS 的个人被视为“晚期检测者”。使用艾滋病毒/艾滋病监测数据对迟到检测者的患病率进行了估计，并报告了很高的迟到检测率。然而，尚未进行评估该定义的研究。我们根据延迟检测的监测定义测量了延迟检测的错误分类程度。方法。我们使用了 2007 年至 2008 年旧金山符合晚期检测定义的人群中 HIV 阴性检测日期，如果在 HIV 诊断后五年内进行了阴性 HIV 检测，则将其重新分类为“已验证的非晚期检测者”；如果之前没有进行过检测，或者如果在诊断前五年或以上记录了阴性检测，则将其重新分类为“已验证的晚期检测者”；或者将其重新分类为“未验证的晚期检测者状态”。我们使用延迟测试的不同定义来测量延迟测试者状态的错误分类和延迟测试的流行率。结果。在艾滋病毒诊断后 12 个月内患上艾滋病的 270 人中，我们发现 89 人 (33.0%) 是经过验证的后期检测者，131 人 (48.5%) 是经过验证的非后期检测者，50 人 (18.5%) 是无法验证的。使用监测定义（HIV 诊断后 12 个月内患上 AIDS 的个人），延迟检测的发生率为 26.3%，而当仅限于经核实为延迟检测者的个人时，该比例为 9.0%。结论。定义艾滋病毒诊断后 12 个月内感染艾滋病的人而不考虑之前的阴性艾滋病毒检测日期会导致后期检测的严重错误分类。
Objective. Individuals diagnosed with AIDS within 12 months of HIV diagnosis have been considered "late testers." Prevalence estimates of late testers have been made using HIV/AIDS surveillance data, and high rates of late testing have been reported. However, studies evaluating this definition have not been conducted. We measured the degree of misclassification of delayed testing based on this surveillance definition of late testing.Methods. We used dates of negative HIV tests among people who met this definition of late testing in San Francisco from 2007 to 2008 to reclassify people as "verified non-late testers" if there was a negative HIV test within five years of HIV diagnosis, as "verified late testers" if there were no prior tests or if negative tests were recorded five or more years prior to diagnosis, or as "late-tester status not verified." We measured misclassification of late-tester status and the prevalence of late testing using the different definitions of late testing.Results. Of the 270 people who developed AIDS within 12 months of HIV diagnosis, we found that 89 (33.0%) were verified late testers, 131 (48.5%) were verified non-late testers, and 50 (18.5%) were unverifiable. Using the surveillance definition (individuals who develop AIDS within 12 months of HIV diagnosis), the prevalence of late testing was 26.3%, whereas it was 9.0% when restricted to individuals verified as late testers.Conclusion. Defining people who develop AIDS within 12 months of HIV diagnosis without taking into consideration the dates of prior negative HIV tests leads to substantial misclassification of late testing.