Reactions and syntheses with organometallic compounds. 7. Synthesis of benzolactams by palladium-catalyzed amidation
Reactions and syntheses with organometallic compounds. 7. Synthesis of benzolactams by palladium-catalyzed amidation
复制标题
DOI：
10.1021/jo00403a013
复制
发表时间：
1978-04
影响因子：
3.6
通讯作者：
M. Mori*;K. Chiba;Y. Ban
中科院分区：
文献类型：
--
作者：
M. Mori*;K. Chiba;Y. Ban
8.过渡金属的羰化反应是一个有用的过程，但该反应通常需要相当剧烈的条件，如高压一氧化碳和高温。2然而，Heck等人。报道了在较温和的条件下，在100℃或更低的温度下，在一氧化碳常压下，钯催化的碳烷氧基化和酰胺化的巧妙过程。3.
8. Carbonylation by means of transition metals is a useful process, but the reaction usually requires rather drastic con-ditions such as a high pressure of carbon monoxide and an elevated temperature. 2 However, Heck et al. reported the ingenious process of palladium-catalyzed carboalkoxylation and amidation under milder conditions at 100 C or lower temperatures in an atmospheric pressure of carbon monox-ide. 3