EYE MOVEMENTS FROM SEMICIRCULAR CANAL NERVE STIMULATION IN CAT
EYE MOVEMENTS FROM SEMICIRCULAR CANAL NERVE STIMULATION IN CAT
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DOI：
10.1177/000348946407300116
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发表时间：
1964-01-01
影响因子：
1.4
通讯作者：
BENDER, MB
中科院分区：
文献类型：
--
作者：
COHEN, B;SUZUKI, J;BENDER, MB
方法：因为即使是少量的巴比妥类药物或其他麻醉剂也会引起前庭-眼神经通路易化驱动的显著降低，所以在记录过程中不使用全身麻醉。总共研究了55只猫。半规管神经的手术入路已经详细描述过了。简而言之，急性实验中使用的动物在乙醚下具有高颈脊髓横断。在局部麻醉下，确定半规管，并在靠近壶腹的每个管的骨壁上制作一个小孔。将双极40 μ搪瓷涂层不锈钢电极插入骨壁和骨内膜之间，并推进，直到尖端靠近壶腹神经。当电极被正确放置时，有可能选择性地刺激单个壶腹神经。用石蜡和丙烯酸树脂粘固剂将电极固定在适当位置。
METHODSBecause administration of even small quantities of barbiturates or other anesthetics causes a marked decrease in facilitatory drives in vestibulo-oculomotor pathways,*'^^ general anesthesia was not used during recording. Fifty-five cats were studied in all. The operative approach to the semicircular canal nerves has been described in detail.* In brief, the animals used in acute experiments had a high cervical spinal cord transection under ether. Under local anesthesia the semi circular canals were identified and a small hole was made in the bony wall of each canal close to the ampulla. Bipolar 40 μ enamel-covered stainless steel electrodes cut flush at the tip were inserted between the bony wall and the endosteum and advanced until the tips lay close to the ampullary nerve. When electrodes were properly placed it was possible to selectively stimulate a single ampullary nerve. Electrodes were fixed in place with paraffin and acrylic resin cement.