Magnetic Resonance Imaging Technique for Visualization of Irregular Cerebrospinal Fluid Motion in the Ventricular System and Subarachnoid Space
Magnetic Resonance Imaging Technique for Visualization of Irregular Cerebrospinal Fluid Motion in the Ventricular System and Subarachnoid Space
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DOI：
10.1016/j.wneu.2016.07.062
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发表时间：
2017-01-01
影响因子：
2
通讯作者：
Kuroda, Kagayaki
中科院分区：
文献类型：
--
作者：
Horie, Tomohiko;Kajihara, Nao;Kuroda, Kagayaki
背景：许多研究表明，脑脊液（CSF）的行为不规则，而不是层流，在不同的CSF空间。我们采用了一种改进的先前已知的磁共振成像技术来可视化不规则的CSF运动。随后，我们评估的有用性和临床意义，目前的method.MATERIALS和方法：正常的CSF运动在10名健康志愿者可视化与动态改进，运动敏感，驱动平衡稳态自由进动技术。随后，CSF运动可视化与修改后的序列应用于3 patient.Results：在健康志愿者中，我们实现了可视化的不规则的脑脊液流量在脑室和椎管，而脑脊液运动减少在颅内蛛网膜下腔的外周部分。在一例病例中，我们证实了患者第三脑室开窗术部位的通畅性。在其他方面，我们验证了建议的序列用于确定脑室或蛛网膜下腔和cyst.CONCLUSIONS之间的通信的有用性：使用本序列，我们得到的图像，加重CSF运动，这主要是由不规则的运动。该方法不需要脉冲触发或复杂的图像后处理，并且允许在选定的整个成像平面中在短时间段内可视化CSF运动。因此，它可以在临床上应用于诊断各种疾病，导致异常的CSF空间。
BACKGROUND: Many studies have shown that cerebrospinal fluid (CSF) behaves irregularly, rather than with laminar flow, in the various CSF spaces. We adapted a modified previously known magnetic resonance imaging technique to visualize irregular CSF motion. Subsequently, we assessed the usefulness and clinical significance of the present method.MATERIALS AND METHODS: Normal CSF motion in 10 healthy volunteers was visualized with the dynamic improved, motion-sensitized, driven-equilibrium steady-state free precession technique. Subsequently, CSF motion visualization with a modified sequence was applied to 3 patients.RESULTS: In healthy volunteers, we achieved visualization of the irregularity of CSF flow in the ventricles and spinal canal, whereas CSF motion was diminished in the peripheral part of the intracranial subarachnoid space. In one case, we confirmed the patency of the patient's third ventriculostomy fenestration site. In the other, we verified the usefulness of the proposed sequence for determining the communication between the ventricle or subarachnoid space and the cyst.CONCLUSIONS: Using the present sequence, we obtained images that accentuated CSF motion, which is largely composed of irregular motion. This method does not require pulse triggering or complex post-processing of images and allows visualization of CSF motion in a short period of time in selected whole imaging planes. It can therefore be applied clinically to diagnose various diseases that cause abnormalities in the CSF space.