The United Kingdom Research study into Ethnicity And COVID-19 outcomes in Healthcare workers (UK-REACH): protocol for a prospective longitudinal cohort study of healthcare and ancillary workers in UK healthcare settings.
The United Kingdom Research study into Ethnicity And COVID-19 outcomes in Healthcare workers (UK-REACH): protocol for a prospective longitudinal cohort study of healthcare and ancillary workers in UK healthcare settings.
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DOI：
10.1136/bmjopen-2021-050647
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发表时间：
2021-09-17
期刊：
影响因子：
2.9
通讯作者：
UK-REACH Study Collaborative Group+
中科院分区：
文献类型：
--
作者：
Woolf K;Melbourne C;Bryant L;Guyatt AL;McManus IC;Gupta A;Free RC;Nellums L;Carr S;John C;Martin CA;Wain LV;Gray LJ;Garwood C;Modhwadia V;Abrams KR;Tobin MD;Khunti K;Pareek M;UK-REACH Study Collaborative Group+
2019冠状病毒病大流行在全球造成了严重的发病率和死亡率，并破坏了经济。风险增加的群体包括卫生保健工作者和少数民族群体。新出现的证据表明，来自少数民族群体的医护人员面临与covid -19相关的不良后果的风险增加。迄今为止，还没有对英国卫生保健工作者或医疗保健机构辅助工作者的这些风险进行大规模分析，按种族或职业分层，并根据混杂因素进行调整。本文报告了英国卫生保健工作者的前瞻性纵向问卷调查研究方案，该研究是英国reach项目（英国卫生保健工作者的种族和COVID-19结果研究）的一部分。基线调查问卷将对英国卫生保健员和医疗保健机构的辅助工作人员以及在英国医疗保健监管机构注册的人员进行调查，并在4个月和8个月进行随访调查问卷。经同意，问卷数据将与25年随访的健康记录相关联。将测试种族与COVID-19临床结果、身心健康以及关键混杂因素/解释变量之间的单变量关联。多变量分析将检验种族和经混杂/解释变量调整的关键结果之间的关联。我们将按族群建立随时间变化的模型，促进对不同族群的绝对和相对风险的理解，以及研究结果的普遍性。该研究已获得卫生研究管理局批准（参考文献20/HRA/4718），风险极小。我们的目标是通过明确的参与者信息，即问卷涉及敏感话题，并且没有义务回答这些或任何其他问题，以及通过提供支持组织链接，来管理参与者对敏感话题问题感到困扰的小风险。研究结果将与向政府提交的报告以及向预印本服务器和同行评议期刊提交的论文一起散发。ISRCTN11811602;Pre-results。
The COVID-19 pandemic has resulted in significant morbidity and mortality and devastated economies globally. Among groups at increased risk are healthcare workers (HCWs) and ethnic minority groups. Emerging evidence suggests that HCWs from ethnic minority groups are at increased risk of adverse COVID-19-related outcomes. To date, there has been no large-scale analysis of these risks in UK HCWs or ancillary workers in healthcare settings, stratified by ethnicity or occupation, and adjusted for confounders. This paper reports the protocol for a prospective longitudinal questionnaire study of UK HCWs, as part of the UK-REACH programme (The United Kingdom Research study into Ethnicity And COVID-19 outcomes in Healthcare workers). A baseline questionnaire will be administered to a national cohort of UK HCWs and ancillary workers in healthcare settings, and those registered with UK healthcare regulators, with follow-up questionnaires administered at 4 and 8 months. With consent, questionnaire data will be linked to health records with 25-year follow-up. Univariate associations between ethnicity and clinical COVID-19 outcomes, physical and mental health, and key confounders/explanatory variables will be tested. Multivariable analyses will test for associations between ethnicity and key outcomes adjusted for the confounder/explanatory variables. We will model changes over time by ethnic group, facilitating understanding of absolute and relative risks in different ethnic groups, and generalisability of findings. The study is approved by Health Research Authority (reference 20/HRA/4718), and carries minimal risk. We aim to manage the small risk of participant distress about questions on sensitive topics by clearly participant information that the questionnaire covers sensitive topics and there is no obligation to answer these or any other questions, and by providing support organisation links. Results will be disseminated with reports to Government and papers submitted to pre-print servers and peer reviewed journals. ISRCTN11811602; Pre-results.