ISLAND HYPERPLASIA IN THE PARTIALLY DEPANCREATIZED RAT
ISLAND HYPERPLASIA IN THE PARTIALLY DEPANCREATIZED RAT
复制标题
部分去胰化大鼠的岛增生
DOI：
10.1210/endo-29-4-577
复制
发表时间：
1941
期刊：
影响因子：
4.8
通讯作者：
A. Marble
中科院分区：
文献类型：
--
作者：
N. Friedman;A. Marble
THE HISTOLOGIC APPEARANCE OF THE ISLANDS OF LANGERHANS in the pancreatic remnants of partially depancreatised animals is the subject of a number of reports. The moststriking change which has been noted is the hydropic de-generation of the beta cells in dogs (1–4). More recently, with reference to rats ren-dered diabetic by subtotal pancreatectomy, Long, Katzin and Fry (5) stated: “The islet tissue of the pancreatic remnants displayed the well-known pathological changes previously described in partially depancreatised dogs. There may be found hyper-trophy and all degrees of islet cell degeneration from the most minor to complete destruction and hyalinization.” It is the purpose of the present report to describe the changes in the pancreas of the partially depancreatized rat in greater detail, and to point out differences between the changes in rats and those observed in dogs.
