Enzymatic and immunochemical estimation of C'1 esterase inhibitor in sera from patients with hereditary angioneurotic edema.

Enzymatic and immunochemical estimation of C'1 esterase inhibitor in sera from patients with hereditary angioneurotic edema.
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遗传性血管神经性水肿患者血清中 C1 酯酶抑制剂的酶学和免疫化学评估。

DOI:
10.3109/00365516909080156
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发表时间:
1969
影响因子:
2.1
通讯作者:
H. Mårtensson
H. Mårtensson
中科院分区:
医学4区
文献类型:
--
作者:
A. Laurell;J. Lindegren;I. Malmros;H. Mårtensson

文献摘要

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C'l酯酶抑制剂的免疫化学和酶促测定显示正常血清和肝素血浆值之间存在相关性,而与EDTA血浆值无关。酶法测定EDTA值低于血清和肝素法测定EDTA值。17例遗传性血管神经性水肿患者中有14例值较低。在其中的3个血清中,两种技术获得的值不一致;3种均表现出较低的抑制能力,但抑制蛋白含量升高或正常。
Immunochemical and enzymatic estimation of C'l esterase inhibitor showed a correlation between the values for normal sera and heparin plasma but not for EDTA plasma. With the enzymatic method, EDTA plasma showed lower values than those obtained with sera and heparin plasma. Low values were found in 14 of 17 patients with hereditary angioneurotic edema. In 3 of these sera the values obtained with the two techniques disagreed; all 3 showed low inhibiting capacity but elevated or normal content of inhibitor protein.