Awareness in dementia: A review of clinical correlates
Awareness in dementia: A review of clinical correlates
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DOI：
10.1080/13607860500143075
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发表时间：
2005-09-01
影响因子：
3.4
通讯作者：
Verhey, F
中科院分区：
文献类型：
--
作者：
Aalten, P;Van Valen, E;Verhey, F
本文提供了一个回顾性文献的临床相关性意识痴呆。大多数不一致的发现与抑郁症和更高水平的意识之间的关联。心境恶劣，而不是严重抑郁症，可能与更高水平的意识有关。焦虑似乎也与更高的意识水平有关。冷漠和精神病经常出现在意识较弱的患者中，并且可能与意识共享共同的神经病理学底物。此外，无意识似乎与日常生活功能的困难，增加照顾者的负担，以及全球痴呆症严重程度的恶化有关。可能影响不确定的数据的因素进行了讨论，是未来的研究方向。
This article provides a review of the literature on clinical correlates of awareness in dementia. Most inconsistencies were found with regard to an association between depression and higher levels of awareness. Dysthymia, but not major depression, is probably related to higher levels of awareness. Anxiety also appears to be related to higher levels of awareness. Apathy and psychosis are frequently present in patients with less awareness, and may share common neuropathological substrates with awareness. Furthermore, unawareness seems to be related to difficulties in daily life functioning, increased caregiver burden, and deterioration in global dementia severity. Factors that may be of influence on the inconclusive data are discussed, as are future directions of research.