Log Odds of Positive Lymph Nodes in Colon Cancer: A Meaningful Ratio-based Lymph Node Classification System
Log Odds of Positive Lymph Nodes in Colon Cancer: A Meaningful Ratio-based Lymph Node Classification System
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DOI：
10.1007/s00268-011-1415-x
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发表时间：
2012-03-01
影响因子：
2.6
通讯作者：
D'Ugo, Domenico
中科院分区：
文献类型：
--
作者：
Persiani, Roberto;Cananzi, Ferdinando C. M.;D'Ugo, Domenico
背景 阳性淋巴结的对数几率（LODDS）定义为阳性和阴性淋巴结数量之比的对数，最近被提议作为外科肿瘤学的新预后指标。本研究的目的是探讨淋巴结分类的LODDS系统是否是比结肠癌患者的肿瘤淋巴结转移（TNM）和淋巴结比率（LNR）分类更准确的预后工具。 材料和方法回顾了258例接受手术切除的结肠癌患者的临床病理数据。淋巴结参数根据国际抗癌联盟/美国联合癌症委员会 (UICC/AJCC) TNM 分期系统进行分类，LNR（LNR0 与比率
Background The log odds of positive lymph nodes (LODDS), defined as the log of the ratio between the numbers of positive and negative lymph nodes, has recently been proposed as a new prognostic index in surgical oncology. The aim of the present study was to investigate whether the LODDS system of lymph node classification was a more accurate prognostic tool than the tumor node metastasis (TNM) and lymph node ratio (LNR) classifications in colon cancer patients.Materials and methods Clinicopathologic data from 258 colon cancer patients who had undergone surgical resection were reviewed. Lymph node parameters were categorized according to the Internation Union Against Cancer/American Joint Cancer Commission (UICC/AJCC) TNM staging system, the LNR (LNR0 with ratio