The association of intraoperative factors with the development of postoperative delirium
The association of intraoperative factors with the development of postoperative delirium
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DOI：
10.1016/s0002-9343(98)00292-7
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发表时间：
1998-11-01
影响因子：
5.9
通讯作者：
Lee, TE
中科院分区：
文献类型：
--
作者：
Marcantonio, ER;Goldman, L;Lee, TE
目得：研究相关的术中因素，包括麻醉途径，血流动力学并发症，失血量，与术后delirium.Patients和方法的发展：我们研究了1,341例50岁及以上的患者承认的主要选择性非心脏手术在学术医疗中心。从病历中获得麻醉途径、术中低血压、心动过缓和心动过速、失血量、输血次数和最低术后红细胞压积的数据。通过使用混乱评估方法进行日常访谈以及根据病历和医院护理强度指数来诊断谵妄。结果：117例（9%）患者发生术后谵妄。麻醉途径和术中血流动力学并发症与谵妄无关。谵妄与术中失血量、术后输血量和术后红细胞压积有关
PURPOSE: To examine the association of intraoperative factors, including route of anesthesia, hemodynamic complications, and blood loss, with the development of postoperative delirium.PATIENTS AND METHODS: We studied 1,341 patients 50 years of age and older admitted for major elective noncardiac surgery at an academic medical center. Data on route of anesthesia, intraoperative hypotension, bradycardia and tachycardia, blood loss, number of blood transfusions, and lowest postoperative hematocrit were obtained from the medical record. Delirium was diagnosed by using daily interviews with the Confusion Assessment Method, as well as from the medical record and the hospital's nursing intensity index.RESULTS: Postoperative delirium occurred in 117 (9%) patients. Route of anesthesia and intraoperative hemodynamic complications were not associated with delirium. Delirium was associated with greater intraoperative blood loss, more postoperative blood transfusions, and postoperative hematocrit