Flexible and multifunctional metal-organic framework as matrix for analysis of small molecules using laser desorption/ionization mass spectrometry
Flexible and multifunctional metal-organic framework as matrix for analysis of small molecules using laser desorption/ionization mass spectrometry
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灵活且多功能的金属有机框架作为基质，用于使用激光解吸/电离质谱分析小分子
DOI：
10.1039/c9cc02611h
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发表时间：
2019
影响因子：
4.9
通讯作者：
Huwei Liu
中科院分区：
文献类型：
--
作者：
Wen Ma;Shuting Xu;Wanpeng Ai;Cheng Lin;Yu Bai;Huwei Liu
通过一种通用的方法制备了多种功能性金属有机骨架（MOFs），并将其作为基质用于激光解吸/电离质谱的小分子分析。其中，半胱氨酸-多功能有机膜具有高亲水性、低背景干扰和独特的尺寸排阻效应，是一种多功能复合材料，可作为一种优良的基质和N-聚糖的高效吸附剂。
A variety of functional metal–organic frameworks (MOFs) were prepared via a universal method and served as matrices in small molecule analysis using laser desorption/ionization mass spectrometry. Among them, cysteine-MOF was found to be a multifunctional composite as an excellent matrix and an efficient adsorbent for N-glycans due to its high hydrophilicity, low background interference and unique size-exclusion effect.