Two-step tuberculin testing in a veterans domiciliary population.

Two-step tuberculin testing in a veterans domiciliary population.
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对退伍军人居住人群进行两步结核菌素测试。

DOI:
10.1097/00007611-198307000-00012
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发表时间:
1983
影响因子:
1.1
通讯作者:
Payne Cb
Payne Cb
中科院分区:
医学4区
文献类型:
--
作者:
Simon Ja;McVicker Sj;Ferrell Cr;Payne Cb

文献摘要

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在俄亥俄州南部的一个医院/医务人员健康项目中,796名退伍军人被安排进行结核菌素测试。使用Mantoux试验,使用5 TU的商业纯化蛋白衍生物(PPD)。根据疾病控制中心(CDC)的建议,在一周后重新检测不显著的反应堆,以检测和定量“助推器现象”。记录了成本数据。在740名受试者中,39.3%的反应大于10 mm的初始频率在两步测试中增加到46.7%。414名受试者中有55名表现出增强效应,比率介于亚拉巴马报告的增强效应与纽约罗切斯特报告的无增强效应之间。两步测试的成本超过了,由一个小的利润率,异烟肼预防性治疗的两步测试检测到的明显转换器的估计成本。
: Seven hundred ninety-six veterans were scheduled for tuberculin testing during a hospital/domiciliary employee health program in southern Ohio. The Mantoux test, using 5 TU of commercial purified protein derivative (PPD) was used. Nonsignificant reactors were retested at one week to detect and quantitate the "booster phenomenon," following Centers for Disease Control (CDC) recommendations. Cost data were recorded. The initial frequency of 39.3% reactions greater than 10 mm in 740 tested subjects increased to 46.7% on two-step testing. Fifty-five of 414 subjects exhibited the booster effect, a rate intermediate between that reported in Alabama and no boosting reported in Rochester, New York. Costs of two-step testing exceeded, by a small margin, estimated costs of isoniazid preventive therapy for apparent converters detected by two-step testing.