Opportunities in Interventional and Diagnostic Imaging by Using High-Performance Low-Field-Strength MRI
Opportunities in Interventional and Diagnostic Imaging by Using High-Performance Low-Field-Strength MRI
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DOI：
10.1148/radiol.2019190452
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发表时间：
2019-11-01
期刊：
影响因子：
19.7
通讯作者：
Balaban, Robert S.
中科院分区：
文献类型：
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作者：
Campbell-Washburn, Adrienne E.;Ramasawmy, Rajiv;Balaban, Robert S.
背景：商用低场强度MRI系统通常没有配备最先进的MRI硬件，并且不适合要求苛刻的成像技术。开发了一种将低场强（0.55 T）与高性能成像技术相结合的MRI系统。目的：评估高性能低场强度MRI系统的应用，特别是MRI引导的金属装置心血管导管，高敏感区域的诊断成像和有效的图像采集策略。材料和方法：将商用1.5 T MRI系统修改为0.55 T，同时保持高性能硬件，屏蔽梯度（45 mT/m; 200 T/m/sec）和先进的成像方法。于2018年1月至2019年4月进行MRI检查。在0.55 T时测量T1、T2和T2*；测量外源性造影剂的松弛度；并对低场优势的临床应用进行了评价。结果：研究参与者共进行83次0.55-T MRI检查（45名女性，平均年龄34岁±13岁）。平均而言，与1.5 T相比，0.55 T时T1缩短32%，T2延长26%，T2*延长40%。在0.55 T时发现9个金属介入装置本质上是安全的(
Background: Commercial low-field-strength MRI systems are generally not equipped with state-of-the-art MRI hardware, and are not suitable for demanding imaging techniques. An MRI system was developed that combines low field strength (0.55 T) with high-performance imaging technology.Purpose: To evaluate applications of a high-performance low-field-strength MRI system, specifically MRI-guided cardiovascular catheterizations with metallic devices, diagnostic imaging in high-susceptibility regions, and efficient image acquisition strategies.Materials and Methods: A commercial 1.5-T MRI system was modified to operate at 0.55 T while maintaining high-performance hardware, shielded gradients (45 mT/m; 200 T/m/sec), and advanced imaging methods. MRI was performed between January 2018 and April 2019. T1, T2, and T2* were measured at 0.55 T; relaxivity of exogenous contrast agents was measured; and clinical applications advantageous at low field were evaluated.Results: There were 83 0.55-T MRI examinations performed in study participants (45 women; mean age, 34 years +/- 13). On average, T1 was 32% shorter, T2 was 26% longer, and T2* was 40% longer at 0.55 T compared with 1.5 T. Nine metallic interventional devices were found to be intrinsically safe at 0.55 T (