Tricarbonyl(eta(6)arene)chromium(0) complexes as chiral auxiliaries: Asymmetric synthesis of beta-aminoesters and beta-lactams by Reformatsky condensation
Tricarbonyl(eta(6)arene)chromium(0) complexes as chiral auxiliaries: Asymmetric synthesis of beta-aminoesters and beta-lactams by Reformatsky condensation
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DOI：
10.1016/0040-4020(96)00156-1
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发表时间：
1996-03-25
期刊：
影响因子：
2.1
通讯作者：
Pilati, T
中科院分区：
文献类型：
--
作者：
Baldoli, C;DelButtero, P;Pilati, T
高度立体选择性的合成(e.E.>；98%)的β-氨基酸酯和β-内酰胺类化合物是使用对映体纯的三羰基(ETA(6)苯乙二胺)铬络合物在超声波促进的Reformsky类型反应中完成的。报道了β-内酰胺类化合物的绝对构型与络合亚胺构型之间的关系。
Highly stereoselective syntheses (e.e. > 98%) of beta-aminoesters and beta-lactams were accomplished using enantiomerically pure tricarbonyl (eta(6)benzaldimine)chromium complexes in a Reformatsky type reaction promoted by ultrasound. A correlation between the configuration of complexed imines and absolute configuration of beta-lactam derivatives is reported.