Gender distribution of adult patients on highly active antiretroviral therapy (HAART) in Southern Africa: a systematic review.
Gender distribution of adult patients on highly active antiretroviral therapy (HAART) in Southern Africa: a systematic review.
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DOI：
10.1186/1471-2458-7-63
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发表时间：
2007-04-25
影响因子：
4.5
通讯作者：
Mataya RH
中科院分区：
文献类型：
--
作者：
Muula AS;Ngulube TJ;Siziya S;Makupe CM;Umar E;Prozesky HW;Wiysonge CS;Mataya RH
艾滋病毒和艾滋病是南部非洲日益严重的公共卫生问题。本区域大多数国家的全国成人艾滋病毒流行率估计超过10%。高效抗逆转录病毒疗法（HAART）的日益普及有可能缓解这种情况。然而，令人关切的是，妇女在获得治疗方案方面可能比男子遇到更多障碍。对文献进行了系统回顾，以描述南部非洲接受高效抗逆转录病毒治疗（HAART）的患者的性别分布。获得了接受治疗的患者数量、平均或中位年龄和性别的数据，并在研究和报告中进行了比较。研究中患者的中位或平均年龄范围为33 - 39岁。南部非洲国家的女性与男性艾滋病毒感染率比率为1.2：1至1.6：1，而接受高效抗逆转录病毒疗法的女性与男性比率为0.8：1至2.3：1。大多数报告的治疗中女性：男性比例超过1.6。总体而言，接受高效抗逆转录病毒疗法的女性多于男性，这并不能仅仅用女性艾滋病毒感染率高于男性来解释。在大多数南部非洲国家，接受艾滋病毒抗逆转录病毒治疗的女性比例高于男性，即使考虑到女性艾滋病毒感染率较高。有必要查明促进妇女获得艾滋病毒治疗的因素。随着该区域越来越多的患者接受高效抗逆转录病毒疗法，继续评估接受高效抗逆转录病毒疗法患者的性别分布将非常重要。
HIV and AIDS are significant and growing public health concerns in southern Africa. The majority of countries in the region have national adult HIV prevalence estimates exceeding 10 percent. The increasing availability of highly active antiretroviral therapy (HAART) has potential to mitigate the situation. There is however concern that women may experience more barriers in accessing treatment programs than men. A systematic review of the literature was carried out to describe the gender distribution of patients accessing highly active antiretroviral therapy (HAART) in Southern Africa. Data on number of patients on treatment, their mean or median age and gender were obtained and compared across studies and reports. The median or mean age of patients in the studies ranged from 33 to 39 years. While female to male HIV infection prevalence ratios in the southern African countries ranged from 1.2:1 to 1.6:1, female to male ratios on HAART ranged from 0.8: 1 to 2.3: 1. The majority of the reports had female: male ratio in treatment exceeding 1.6. Overall, there were more females on HAART than there were males and this was not solely explained by the higher HIV prevalence among females compared to males. In most Southern African countries, proportionally more females are on HIV antiretroviral treatment than men, even when the higher HIV infection prevalence in females is accounted for. There is need to identify the factors that are facilitating women's accessibility to HIV treatment. As more patients access HAART in the region, it will be important to continue assessing the gender distribution of patients on HAART.
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DOI：
10.1097/00126334-200405010-00010
发表时间：
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影响因子：
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发表时间：
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影响因子：
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