NtcA-dependent expression of the devBCA operon,: encoding a heterocyst-specific ATP-binding Cassette Transporter in Anabaena spp.
NtcA-dependent expression of the devBCA operon,: encoding a heterocyst-specific ATP-binding Cassette Transporter in Anabaena spp.
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DOI：
10.1128/jb.183.12.3795-3799.2001
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发表时间：
2001-06-01
影响因子：
3.2
通讯作者：
Maldener, I
中科院分区：
文献类型：
--
作者：
Fiedler, G;Muro-Pastor, AM;Maldener, I
devBCA操纵子，编码ATP结合盒输出子的亚基，是鱼腥藻中固氮异形胞分化所必需的。氮缺乏依赖性转录的操纵子和使用其转录起始点，位于762（鱼腥藻菌株ATCC 29413-FD）或704（鱼腥藻属菌株PCC 7120）bp的翻译起始位点上游，被发现需要全局氮转录调节剂NtcA。此外，NtcA被证明在体外结合devBCA的启动子。
The devBCA operon, encoding subunits of an ATP-binding cassette exporter, is essential for differentiation of N-2-fixing heterocysts in Anabaena spp. Nitrogen deficiency-dependent transcription of the operon and the use of its transcriptional start point, located 762 (Anabaena variabilis strain ATCC 29413-FD) or 704 (Anabaena sp. strain PCC 7120) bp upstream of the translation start site, were found to require the global nitrogen transcriptional regulator NtcA. Furthermore, NtcA was shown to bind in vitro to the promoter of devBCA.