Physical activity recommendations and decreased risk of mortality
Physical activity recommendations and decreased risk of mortality
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DOI：
10.1001/archinte.167.22.2453
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发表时间：
2007-12-10
影响因子：
--
通讯作者：
Schatzkin, Arthur
中科院分区：
文献类型：
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作者：
Leitzmann, Michael F.;Park, Yikyung;Schatzkin, Arthur
背景资料：无论是国家的体力活动的建议与死亡率benefit.Methods：我们前瞻性地研究了体力活动的指导方针之间的死亡率252 925名妇女和男子年龄在50至71岁的美国国立卫生研究院-美国退休人员协会（NIH-AARP）饮食与健康研究。体力活动进行了评估，使用2个自我管理的基线questionnaire.Results：在1 265 347人年的后续行动，7900名参与者死亡。与不活动相比，达到接近中度活动建议的活动水平（每周大部分时间至少30分钟）或剧烈运动（每周至少20分钟3次）与27%的（相对危险度[RR]，0.73; 95%可信区间[ CI]，0.68-0.78）和32%（RR，0.68; 95% CI，0.64-0.73）分别降低死亡风险。符合这两项建议的体力活动与总体死亡风险的大幅降低有关（RR，0.50; 95% CI，0.46-0.54）和亚组，包括吸烟者（RR，0.48; 95% CI，0.44-0.53）和非吸烟者（RR，0.54; 95% CI，0.45-0.64），正常体重（RR，0.45; 95% CI，0.39-0.52）和超重或肥胖个体（RR，0.48; 95%CI，0.44-0.54），2 h/d（RR，0.53; 95%CI，0.44-0.63）和超过2 h/d看电视或视频（RR，0.50; 95%CI，0.45-0.55）。从事低于推荐水平的体力活动也与降低死亡风险有关（RR，0.81; 95%CI，0.76-0.86）。结论：遵循体力活动指南与降低死亡风险相关。减少死亡率也可以通过从事低于建议的活动水平来实现。
Background: Whether national physical activity recommendations are related to mortality benefit is incompletely understood.Methods: We prospectively examined physical activity guidelines in relation to mortality among 252 925 women and men aged 50 to 71 years in the National Institutes of Health-American Association of Retired Persons (NIH-AARP) Diet and Health Study. Physical activity was assessed using 2 self-administered baseline questionnaires.Results: During 1 265 347 person-years of follow-up, 7900 participants died. Compared with being inactive, achievement of activity levels that approximate the recommendations for moderate activity ( at least 30 minutes on most days of the week) or vigorous exercise ( at least 20 minutes 3 times per week) was associated with a 27% ( relative risk [RR], 0.73; 95% confidence interval [ CI], 0.68-0.78) and 32% ( RR, 0.68; 95% CI, 0.64-0.73) decreased mortality risk, respectively. Physical activity reflective of meeting both recommendations was related to substantially decreased mortality risk overall ( RR, 0.50; 95% CI, 0.46-0.54) and in subgroups, including smokers ( RR, 0.48; 95% CI, 0.44-0.53) and nonsmokers ( RR, 0.54; 95% CI, 0.45-0.64), normal weight ( RR, 0.45; 95% CI, 0.39-0.52) and overweight or obese individuals ( RR, 0.48; 95% CI, 0.44-0.54), and those with 2 h/d ( RR, 0.53; 95% CI, 0.44-0.63) and more than 2 h/d of television or video watching ( RR, 0.50; 95% CI, 0.45-0.55). Engaging in physical activity at less than recommended levels was also related to reduced mortality risk ( RR, 0.81; 95% CI, 0.76-0.86).Conclusions: Following physical activity guidelines is associated with lower risk of death. Mortality benefit may also be achieved by engaging in less than recommended activity levels.