Chlamydia pneumoniae infection of the central nervous system
Chlamydia pneumoniae infection of the central nervous system
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DOI：
10.1097/00019052-200106000-00015
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发表时间：
2001-06-01
影响因子：
4.8
通讯作者：
Sriram, S
中科院分区：
文献类型：
--
作者：
Yucesan, C;Sriram, S
肺炎衣原体是一种常见的呼吸道病原体，目前与许多慢性疾病有关。该生物体可以感染血管内皮、巨噬细胞和平滑肌细胞，这表明它可能在许多全身性疾病中发挥作用。本综述的重点是中枢神经系统也可能是该药物的目标的可能性。肺炎衣原体对神经组织的趋向性表明它可能在多种神经系统疾病中发挥作用，包括阿尔茨海默病、多发性硬化症和巨细胞动脉炎。当前神经学观点 14：355-359。 (C) 2001 年利平科特威廉姆斯和威尔金斯。
Chlamydia pneumoniae is a common respiratory pathogen that is now being implicated in a number of chronic diseases. That the organism can infect vascular endothelium, macrophages and smooth muscle cells suggests that it may play a role in many systemic diseases. The present review focuses on the possibility that the central nervous system can also be a target of this agent. The tropism of C. pneumoniae to the neural tissue suggests it may play a role in diverse neurologic diseases, including Alzheimer's disease, multiple sclerosis and giant-cell arteritis. Curr Opin Neurol 14:355-359. (C) 2001 Lippincott Williams & Wilkins.