Targeted disruption of tumor vasculature with a multi-mutated,replication-competent type I herpes simplex virus (HSV-1) expressing RS1 gene under the control of smooth muscle-specific human calponin promoter.

Targeted disruption of tumor vasculature with a multi-mutated,replication-competent type I herpes simplex virus (HSV-1) expressing RS1 gene under the control of smooth muscle-specific human calponin promoter.
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在平滑肌特异性人钙调蛋白启动子的控制下,表达 RS1 基因的多突变、具有复制能力的 I 型单纯疱疹病毒 (HSV-1) 有针对性地破坏肿瘤血管系统。

DOI:
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发表时间:
2003
期刊:
Molecular Therapy 7
影响因子:
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通讯作者:
K.
K.
中科院分区:
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文献类型:
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作者:
Yamamura;H.;Takahashi;K.

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