Fundamental Study on Near-Axis Scattered Light and Its Application to Optical Computed Tomography
Fundamental Study on Near-Axis Scattered Light and Its Application to Optical Computed Tomography
复制标题
近轴散射光的基础研究及其在光学计算机断层扫描中的应用
DOI：
10.1007/s10043-000-0383-4
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发表时间：
2000
期刊：
影响因子：
1.2
通讯作者：
M. Kitama
中科院分区：
文献类型：
--
作者：
K. Shimizu;M. Kitama
为了找到光学计算机断层扫描（光学CT）的基本原理，对漫随机介质中散射光的利用进行了基础研究。我们将沿入射光束的光轴沿着传播的散射光称为近轴散射光（NASL）。提出了利用NASL对扩散介质进行成像的方法，分析了NASL的基本特性。通过仿真和测量，证实了非线性系统的存在性和可测性。为了有效地检测NASL，开发了一种称为散射角微分技术的技术。在模型体模的CT成像中，验证了该方法的可行性和有效性。我们发现，这种技术本身是不够的，以获得一个动物身体的横截面图像，因此，一种技术称为接触技术的设计，以克服在空气组织界面的反射和折射的问题。最后，开发了一个原型系统，其中集成了所有提出的技术。利用该系统，我们可以获得活体小鼠的CT图像，其中富含血液的器官如肝脏和肾脏可以清楚地识别。
To find a basic principle of optical computed tomography (optical CT), a fundamental study was conducted on the use of scattered light in diffuse random media. We call the scattered light that propagates along the optical axis of the incident light beam near-axis scattered light (NASL). The use of NASL for the imaging through a diffuse medium was proposed and its basic characteristics were analyzed. The existence and measurability of NASL were confirmed in the simulation and measurement. To detect NASL efficiently, a technique called the scattering angle differential technique was developed. In CT imaging with a model phantom, the feasibility and effectiveness of the proposed technique were verified. We found that this technique alone was not sufficient to obtain the cross sectional image of an animal body, therefore a technique called the contact technique was devised to overcome the problems of reflection and refraction at the air-tissue interface. Finally, a prototype system was developed which integrated all the proposed techniques. With this system, we could obtain the CT images of a living mouse, in which the blood-rich organs such as liver and kidneys were clearly recognizable.
相干探测成像方法对小鼠腿部进行活体激光断层成像
DOI：
--
发表时间：
2003
期刊：
Optical Review Vol.10,No.5
影响因子：
--
作者：
S.Tanosaki;Y.Sasaki;Yuasa;T.Akatsuka;et al.
通讯作者：
et al.