Dipstick haematuria and bladder cancer in men over 60: results of a community study.
Dipstick haematuria and bladder cancer in men over 60: results of a community study.
复制标题
60 岁以上男性的试纸血尿和膀胱癌：一项社区研究的结果。
作者：
J. P. Britton;A. Dowell;P. Whelan
目的：调查社区一组男性试纸血尿的患病率及其相关性。设计：前瞻性研究邀请老年人到健康中心进行尿液筛查，作为健康检查的一部分。环境——利兹市内的一家健康中心。受试者：578名年龄在60-85岁之间的855名男性响应了参与邀请。干预措施-受试者用试纸（Multistix）检测尿液是否存在血液，然后在接下来的10周内每周检测一次尿液。有一个或多个阳性检测结果的患者接受全面的泌尿学检查。主要结局指标：尿样血尿患者中泌尿系统疾病的患病率。结果：78名男性（13%）在单次检测中出现试纸血尿，另有54名男性（9%）在随后的10周内每周检测一次尿时出现试纸血尿。在87名男性的调查中，45人发现泌尿系统疾病，其中4人患有膀胱肿瘤，7人患有上皮发育不良。结论：试纸血尿是60岁以上男性常见的偶然发现，与明显的泌尿系统疾病相关。微创检查方法的引入，特别是灵活的膀胱镜检查和超声检查，使对这些患者的检查变得简单和安全，并使在社区进行膀胱癌筛查更加可行。
OBJECTIVE--To investigate the prevalence and relevance of dipstick haematuria in a group of men in the community. DESIGN--Prospective study of elderly men invited to attend a health centre for urine screening as part of a health check. SETTING--An inner city health centre in Leeds. SUBJECTS--578 Of 855 men aged 60-85 responding to an invitation to participate. INTERVENTIONS--The subjects had their urine tested with a dipstick (Multistix) for the presence of blood and then tested their urine once a week for the next 10 weeks. Those with one or more positive test results were offered full urological investigation. MAIN OUTCOME MEASURE--The prevalence of urological disease in those subjects with dipstick haematuria. RESULTS--78 Men (13%) had dipstick haematuria on a single test and a further 54 (9%) had evidence of dipstick haematuria when testing their urine once a week during a subsequent 10 week period. Investigation of 87 men disclosed urological disease in 45, including four with a bladder tumour and seven with epithelial dysplasia. CONCLUSION--Dipstick haematuria is a common incidental finding in men over 60 and is associated with appreciable urological disease. The introduction of less invasive methods of investigation, particularly flexible cystoscopy and ultrasonography, has made investigation of these patients simple and safe and makes screening for bladder cancer in the community more feasible.