Transcription initiation is localized to a TATAless region in the ovine beta 1 adrenergic receptor gene.
Transcription initiation is localized to a TATAless region in the ovine beta 1 adrenergic receptor gene.
复制标题
转录起始位于绵羊 β1 肾上腺素能受体基因的 TATAless 区域。
DOI：
10.1006/bbrc.1995.1804
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发表时间：
1995
期刊：
影响因子：
--
通讯作者：
Waschek,JA
中科院分区：
文献类型：
--
作者：
Padbury,JF;Tseng,YT;Waschek,JA
We cloned and sequenced the ovine beta1adrenergic receptor (β1AR) gene and promoter region. The transcription start site was localized by RNase protection and primer extension to a GC-rich region. The predominant initiation sequence did not resemble an initiator element and there was no upstream TATA box. Sequence analysis revealed several potential thyroid hormone and glucocorticoid regulatory elements. Identification of the promoter structure of this important gene will help define its novel regulation during development.
