Effect of Flavors and Modified Risk Messages on E-cigarette Abuse Liability.
Effect of Flavors and Modified Risk Messages on E-cigarette Abuse Liability.
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DOI：
10.18001/trs.3.4.1
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发表时间：
2017-10
影响因子：
--
通讯作者：
Cobb CO
中科院分区：
文献类型：
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作者：
Barnes AJ;Bono RS;Lester RC;Eissenberg TE;Cobb CO
在符合监管的风味和信息条件下，衡量电子烟与传统烟草香烟的滥用倾向。两项研究使用了2×2的受试者内设计，考虑了电子烟的味道因素(研究1：烟草与薄荷醇；研究2：樱桃与无香料)和信息(研究1：减少危害与不信息；研究2：减少接触致癌物与不信息)与吸烟者(N(总数)=36)。线性混合效应模型评估了烟草产品的滥用责任。结果包括多项选择程序(MCP)和卷烟购买任务(CPT)得出的消费为零(参与者愿意为烟草产品支付的最大金额)的价格以及CPT的需求弹性(价格敏感度)。在MCP中，与香烟(P<；0.05)相比，在所有电子烟条件下，消费达到零的价格显著低于香烟(P<；0.05)，但烟草口味(短信或无短信)除外。与香烟相比，薄荷醇/无信息和无香料/减少暴露信息条件的需求弹性显著更高(p<；0.05)。电子烟中包含的香料和修改后的风险信息可能会影响吸烟者滥用电子烟的倾向，这表明监管途径可能会影响对传统和替代烟草产品的需求。
To measure e-cigarettes’ abuse liability compared to conventional tobacco cigarettes under flavor and message conditions amenable to regulation. Two studies used 2×2 within-subjects designs with factors of e-cigarette flavor (Study 1: tobacco vs. menthol; Study 2: cherry vs. unflavored) and message (Study 1: reduced harm vs. no message; Study 2: reduced exposure to carcinogens vs. no message) with cigarette smokers (N(total) = 36). Linear mixed effects models assessed abuse liability for tobacco products. Outcomes included the price after which consumption is zero (the maximum amount participants would pay for a tobacco product) from the multiple choice procedure (MCP) and cigarette purchase task (CPT) and demand elasticity (price sensitivity) from the CPT. In the MCP, the price where consumption reached zero was significantly lower in all e-cigarette conditions except tobacco flavor (message or no message) compared to cigarettes (p < .05 each). Demand elasticity was significantly higher for menthol/no message and unflavored/reduced exposure message conditions relative to cigarettes (p < .05 each). Flavors and modified risk messages included with e-cigarettes may affect e-cigarette abuse liability among smokers, suggesting regulatory pathways to influence demand for conventional and alternative tobacco products.