Synthesis of Hsp90 dimerization modulators
Synthesis of Hsp90 dimerization modulators
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DOI：
10.1016/j.bmcl.2006.03.092
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发表时间：
2006-07-01
影响因子：
2.7
通讯作者：
Nicchitta, Christopher V.
中科院分区：
文献类型：
--
作者：
Chiosis, Gabriela;Aguirre, Julia;Nicchitta, Christopher V.
介绍了几种热休克蛋白90（Hsp 90）二聚化化学调节剂的合成和评价。这些试剂可能代表有用的工具，研究的重要性，N-末端二聚化，也确定亚基接口（S）在热休克蛋白90。(c)2006爱思唯尔有限公司保留所有权利。
The synthesis and evaluation of several chemical modulators of heat shock protein 90 (Hsp90) dimerization is presented. These agents may represent useful tools to study the importance of N-terminal dimerization and also to determine subunit interface(s) in Hsp90. (c) 2006 Elsevier Ltd. All rights reserved.