Partner proteins determine multiple functions of Hsp70.
Partner proteins determine multiple functions of Hsp70.
复制标题
伙伴蛋白决定 Hsp70 的多种功能。
DOI：
10.1016/0962-8924(95)80013-7
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发表时间：
1995
影响因子：
19
通讯作者：
N. Pfanner
中科院分区：
文献类型：
--
作者：
J. Rassow;W. Voos;N. Pfanner
The 70 kDa heat shock proteins (Hsp70s) are ubiquitous molecular chaperones that are best known for their participation in protein folding. However, evidence is accumulating that Hsp70s perform several other cellular functions in cooperation with specific soluble or membrane-bound partner proteins. While the basic function of Hsp70s is explained by their ability to bind unfolded polypeptide segments, the partner proteins appear to customize them for specific roles such as involvement in protein traffic and folding, translocation of preproteins across membranes, and gene regulation.
