Diarrheal disease risk in Matlab, Bangladesh

Diarrheal disease risk in Matlab, Bangladesh
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DOI:
10.1016/s0277-9536(99)00146-x
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发表时间:
1999-08-01
影响因子:
5.4
通讯作者:
Emch, M
Emch, M
中科院分区:
医学2区
文献类型:
--
作者:
Emch, M

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该研究项目的目标是通过分析生物、社会经济、文化/行为和环境因素随时间和空间的复杂和动态相互作用,评估孟加拉国农村地区疟疾的风险。计算了霍乱和非霍乱性水霍乱的危险因素,比较了几个自变量的相对危险性。收集了1992年1月1日至1994年12月31日在国际腹泻病研究中心(ICDDR)医院住院的患者的腹泻病数据。使用实验室和医院记录,病例被分配到两个腹泻疾病类别(霍乱或非霍乱水样腹泻)之一,作为研究分析阶段的因变量。从社区中随机选择与之匹配的个体作为对照。收集假设与水样腹泻相关的独立变量的信息。这些信息是通过发放调查问卷、从ICDDR的人口监测系统记录和社区卫生工作者记录簿中获得二级数据以及使用地理信息系统数据库计算变量来收集的。卫生和水的供应和使用对于减少继发性霍乱和非霍乱、水泻传播的努力极为重要。水的使用和可用性变量对非霍乱水源性霍乱风险比霍乱更重要,但它们对两者都很重要。社会经济地位是这两种疾病的重要间接原因,因为贫穷是许多其他变量的根源,如缺乏卫生设施和清洁用水。洪水控制与这两种类型的腹泻有关,但原因尚不清楚。由于孟加拉国洪水行动计划将继续建设和维护防洪设施,因此调查全国范围内这种关系是否存在模式以及调查这种关系存在的原因非常重要。(C)1999爱思唯尔科技有限公司。保留所有权利。
The objective of this research project is to assess risk for diarrheal disease in rural Bangladesh by analyzing the complex and dynamic interaction of biological, socioeconomic, cultural/behavioral and environmental factors over time and space. Risk factors of cholera and non-cholera water diarrheal disease are calculated to compare the relative importance of risk for several independent variables. Diarrheal disease data were collected for people who were hospitalized at the International Centre for Diarrhoeal Disease Research (ICDDR) hospital from January 1, 1992 to December 31, 1994. Using laboratory and hospital records, cases were assigned to one of two diarrhea disease categories (cholera or non-cholera watery diarrhea) that were used as dependent variables in the analysis stage of the research. Age-matched individuals were randomly chosen from the community to be controls. Information was collected for independent variables that were hypothesized to be related to watery diarrhea. This information was collected by administering questionnaires, obtaining secondary data from the ICDDR's demographic surveillance system records and community health worker record books and calculating variables using a geographic information system database. Sanitation and water availability and use are extremely important in the effort to reduce secondary cholera and non-cholera, watery diarrhea transmission. Water use and availability variables were more important for non-cholera watery diarrheal risk than for cholera but nevertheless they were important for both. Socioeconomic status is an important indirect cause of both of these diseases because poverty is the root cause of many of the other variables, such as lack of sanitation and clean water. Flood-control was related to both types of diarrhea but it is not understood why. Since the Bangladesh Flood Action Plan will continue to build and maintains flood-control embankments, it is important to investigate whether there is a pattern to this relationship throughout the country and to investigate why the relationship exists. (C) 1999 Elsevier Science Ltd. All rights reserved.