SMOKING, SMOKING CESSATION, AND MAJOR DEPRESSION
SMOKING, SMOKING CESSATION, AND MAJOR DEPRESSION
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DOI：
10.1001/jama.264.12.1546
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发表时间：
1990-09-26
影响因子：
120.7
通讯作者：
JOHNSON, J
中科院分区：
文献类型：
--
作者：
GLASSMAN, AH;HELZER, JE;JOHNSON, J
吸烟和抑郁症之间的关系在以前的工作中提出，涉及非随机选择的样本。我们使用美国国家心理健康研究所的圣刘易斯流行病学流域调查1980年至1983年间收集的基于人群的数据（n = 3213）对这种关联进行了检验。经常吸烟的历史中观察到更频繁的个人谁经历过严重的抑郁症在他们的生活中的一段时间比谁从未经历过严重的抑郁症或没有精神病诊断的个人。患有严重抑郁症的吸烟者在尝试戒烟时也不如对照组成功。在较大的人群中观察到的吸烟率和戒烟率的性别差异在抑郁症组中并不明显。此外，吸烟和重度抑郁症之间的关联并不普遍存在于所有精神病诊断中。引用的其他数据表明，当有抑郁症史的人停止吸烟时，抑郁症状，在某些情况下，严重的重度抑郁症可能会随之而来。
A relationship between cigarette smoking and major depressive disorder was suggested in previous work involving nonrandomly selected samples. We conducted a test of this association, employing population-based data (n = 3213) collected between 1980 and 1983 in the St Louis Epidemiologic Catchment Area Survey of the National Institute of Mental Health. A history of regular smoking was observed more frequently among individuals who had experienced major depressive disorder at some time in their lives than among individuals who had never experienced major depression or among individuals with no psychiatric diagnosis. Smokers with major depression were also less successful at their attempts to quit than were either of the comparison groups. Gender differences in rates of smoking and of smoking cessation observed in the larger population were not evident among the depressed group. Furthermore, the association between cigarette smoking and major depression was not ubiquitous across all psychiatric diagnoses. Other data are cited indicating that when individuals with a history of depression stop smoking, depressive symptoms and, in some cases, serious major depression may ensue.