Postnatal Inflammation in the Pathogenesis of Bronchopulmonary Dysplasia
Postnatal Inflammation in the Pathogenesis of Bronchopulmonary Dysplasia
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DOI：
10.1002/bdra.23220
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发表时间：
2014-03-01
影响因子：
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通讯作者：
Bhandari, Vineet
中科院分区：
文献类型：
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作者：
Bhandari, Vineet
暴露于高氧、有创机械通气和全身/局部脓毒症是支气管肺发育不良 (BPD) 发病机制中产后炎症的重要先决条件。这篇综述将总结从动物（狒狒、羔羊/绵羊、大鼠和小鼠）模型中获得的信息，这些信息涉及使早产儿容易患 BPD 的特定炎症因子和信号分子。出生缺陷研究（A 部分）100:189-201，2014 年。(c) 2014 Wiley periodicals, Inc.
Exposure to hyperoxia, invasive mechanical ventilation, and systemic/local sepsis are important antecedents of postnatal inflammation in the pathogenesis of bronchopulmonary dysplasia (BPD). This review will summarize information obtained from animal (baboon, lamb/sheep, rat and mouse) models that pertain to the specific inflammatory agents and signaling molecules that predispose a premature infant to BPD. Birth Defects Research (Part A) 100:189-201, 2014. (c) 2014 Wiley Periodicals, Inc.