A New Vascular Coupler Design for End-to-End Anastomosis: Fabrication and Proof-of-Concept Evaluation
A New Vascular Coupler Design for End-to-End Anastomosis: Fabrication and Proof-of-Concept Evaluation
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DOI：
10.1115/1.4029924
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发表时间：
2015-09-01
影响因子：
0.9
通讯作者：
Agarwal, Jay
中科院分区：
文献类型：
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作者：
Li, Huizhong;Gehrke, Cody;Agarwal, Jay
传统的手工缝合血管连接技术耗时、昂贵，并且需要高度复杂的仪器和技术专业知识。本研究的目的是开发一种新的血管耦合器，可以以更简单、更有效的方式用于动脉和静脉的端对端吻合手术。血管耦合器有四个可旋转翼，每个翼上有一个可平移钉。原型采用聚四氟乙烯 (PTFE) 和高密度聚乙烯 (HDPE) 制造。设计了一套安装工具来促进吻合过程。使用塑料管和猪尸体血管对血管耦合器进行的概念验证测试表明，耦合器应按设计工作。简化的有限元 (FE) 模型有助于评估耦合器安装过程中人体血管撕裂的可能性。对耦合器的测试结果表明，该血管耦合器能够与血管有效附着，吻合后不渗漏，具有足够的接合强度，对血管内血流影响较小。使用血管耦合器连接猪尸体血管，整个吻合过程可在3分钟内完成。
Traditional hand-suturing for vascular connection techniques is time consuming, expensive, and requires highly complex instruments and technical expertise. The aim of this study is to develop a new vascular coupler that can be used in end-to-end anastomosis surgery in an easier and more efficient way for both arteries and veins. The vascular coupler has four rotatable wings and one translatable spike in each wing. Prototypes were manufactured using polytetrafluoroethylene (PTFE) and high-density polyethylene (HDPE). A set of installation tools was designed to facilitate the anastomosis process. Proof-of-concept testing with the vascular coupler using plastic tubes and porcine cadaver vessels showed that the coupler should work as designed. A simplified finite element (FE) model assisted in the evaluation of the tearing likelihood of human vessels during installation of the coupler. Results of tests on the coupler showed that the vascular coupler could be efficiently attached to blood vessels, did not leak after the anastomosis was performed, had sufficient joint strength, and had little impact on flow in the vessel. The entire anastomosis process can be completed in 3 min when using the vascular coupler to join porcine cadaver vessels.