Recent advances in direct current electrokinetic manipulation of particles for microfluidic applications

Recent advances in direct current electrokinetic manipulation of particles for microfluidic applications
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DOI:
10.1002/elps.201900048
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发表时间:
2019-09
期刊:
影响因子:
2.9
通讯作者:
X. Xuan
X. Xuan
中科院分区:
生物学3区
文献类型:
--
作者:
X. Xuan

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微流体装置已被广泛用于许多应用中实现各种颗粒的精确输送和放置。到目前为止,已经证明了一系列力场可以控制微通道中颗粒的运动。其中,电场驱动的粒子操纵可能是最受欢迎和最通用的技术,因为它具有普遍的适用性和适应性,以及易于操作和集成到芯片实验室系统中。本文综述了直流电(DC)(以及直流偏置交流电)电动操纵微流体应用中的粒子的最新进展。电压通过电极施加,所述电极定位在远端通道端储液器中,用于悬浮流体的同时输送和悬浮颗粒的操纵。本文重点介绍了流体线性电渗流中的跨流非线性动电运动,通过壁诱导的电提升和/或绝缘结构诱导的介电泳力实现了微通道中粒子输运的多样性控制。
Microfluidic devices have been extensively used to achieve precise transport and placement of a variety of particles for numerous applications. A range of force fields have thus far been demonstrated to control the motion of particles in microchannels. Among them, electric field‐driven particle manipulation may be the most popular and versatile technique because of its general applicability and adaptability as well as the ease of operation and integration into lab‐on‐a‐chip systems. This article is aimed to review the recent advances in direct current (DC) (and as well DC‐biased alternating current) electrokinetic manipulation of particles for microfluidic applications. The electric voltages are applied through electrodes that are positioned into the distant channel‐end reservoirs for a concurrent transport of the suspending fluid and manipulation of the suspended particles. The focus of this review is upon the cross‐stream nonlinear electrokinetic motions of particles in the linear electroosmotic flow of fluids, which enable the diverse control of particle transport in microchannels via the wall‐induced electrical lift and/or the insulating structure‐induced dielectrophoretic force.