Effects of post-encoding stress on performance in the DRM false memory paradigm.

Effects of post-encoding stress on performance in the DRM false memory paradigm.
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DOI:
10.1101/lm.039354.115
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发表时间:
2016-01
期刊:
Learning & memory (Cold Spring Harbor, N.Y.)
影响因子:
--
通讯作者:
Payne JD
Payne JD
中科院分区:
其他
文献类型:
--
作者:
Pardilla-Delgado E;Alger SE;Cunningham TJ;Kinealy B;Payne JD

文献摘要

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许多研究已经研究了压力如何影响真实记忆,但压力如何影响错误记忆的形成仍然知之甚少。为了具体地针对记忆巩固,在编码15个中性的语义相关的单词列表(DRM错误记忆任务)之后施用心理社会应激(TSST)或控制操纵,并且在24小时后测试记忆。压力降低识别的研究词,而增加错误识别的语义相关的诱惑词。此外,虽然控制组受试者记住的真实和虚假的话相等,强调主题记住更多的虚假比真实的话。这些结果表明,在DRM任务中,压力支持要点记忆的形成,可能是通过阻碍海马体中的细节特异性处理。
Numerous studies have investigated how stress impacts veridical memory, but how stress influences false memory formation remains poorly understood. In order to target memory consolidation specifically, a psychosocial stress (TSST) or control manipulation was administered following encoding of 15 neutral, semantically related word lists (DRM false memory task) and memory was tested 24 h later. Stress decreased recognition of studied words, while increasing false recognition of semantically related lure words. Moreover, while control subjects remembered true and false words equivalently, stressed subjects remembered more false than true words. These results suggest that stress supports gist memory formation in the DRM task, perhaps by hindering detail-specific processing in the hippocampus.