Persistent gamma oscillations in superficial layers of rat auditory neocortex: experiment and model

Persistent gamma oscillations in superficial layers of rat auditory neocortex: experiment and model
复制标题

大鼠听觉新皮层表层的持续伽马振荡:实验和模型

DOI:
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发表时间:
2005
期刊:
Journal of Physiology
影响因子:
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通讯作者:
M. Whittington
M. Whittington
中科院分区:
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文献类型:
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作者:
R. Traub;A. Bibbig;F. LeBeau;M. Cunningham;M. Whittington

文献摘要

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Eberhard Buhl 及其合作者于 1998 年发现了由卡巴胆碱和红藻氨酸(以及其他药物)浴液诱导的持续体外伽马振荡。这种振荡非常强劲,可以持续数小时;但振荡的机制也很复杂:它们依赖于阶段性突触兴奋和抑制,依赖于中间神经元之间和锥体神经元之间的电耦合,并且——至少在新皮质中——它们依赖于一些神经元复杂的内在特性。
Persistent in vitro gamma oscillations, induced by bath application of carbachol and kainate (amongst other drugs), were discovered by Eberhard Buhl and collaborators in 1998. The oscillations are robust, in that they can continue for hours; but the oscillations are also intricate in their mechanisms: they depend upon phasic synaptic excitation and inhibition, upon electrical coupling between interneurones and between pyramidal neurones, and – at least in neocortex – they depend upon complex intrinsic properties of some of the neurones.