An Analysis of the Components of Pain, Function, and Health-Related Quality of Life in Patients with Failed Back Surgery Syndrome Treated with Spinal Cord Stimulation or Conventional Medical Management
An Analysis of the Components of Pain, Function, and Health-Related Quality of Life in Patients with Failed Back Surgery Syndrome Treated with Spinal Cord Stimulation or Conventional Medical Management
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DOI：
10.1111/j.1525-1403.2009.00271.x
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发表时间：
2010-07-01
期刊：
影响因子：
2.8
通讯作者：
Taylor, Rod S.
中科院分区：
文献类型：
--
作者：
Eldabe, Sam;Kumar, Krishna;Taylor, Rod S.
目的：尽管解剖学上手术成功，但腰椎手术失败综合征（FBSS）患者仍会经历疼痛、功能障碍和健康相关生活质量（HRQoL）降低。检查子维度的健康结果measurements提供了洞察到patient wellbeing.Materials和Methods：国际多中心PROCESS试验收集详细的HRQoL（EuroQol-5D;短表36）和功能（奥斯韦斯特里残疾指数）100 FBSS patients.Results的信息：在基线，患者报告中度至重度腿部和背部疼痛的不利影响的功能和HRQoL的所有方面。与单独的传统药物治疗相比，还接受脊髓刺激（SCS）的患者报告了6个月时总体和大多数子组分评分的上级疼痛缓解、功能和HRQoL。SCS组的这些改善大多持续到24个月。尽管如此，36-40%的患者经历了持续的显着残疾（站立，升降）和HRQoL问题（疼痛/不适）。结论：长期的患者管理和研究必须集中在这些顽固性FBSS患者的功能和HRQoL结果持续不佳。
Objectives:Failed back surgery syndrome (FBSS) patients experience pain, functional disability, and reduced health-related quality of life (HRQoL) despite anatomically successful surgery. Examining sub-dimensions of health outcomes measures provides insight into patient well-being.Materials and Methods:The international multicenter PROCESS trial collected detailed HRQoL (EuroQol-5D; Short-Form 36) and function (Oswestry Disability Index) information on 100 FBSS patients.Results:At baseline, patients reported moderate-to-severe leg and back pain adversely affecting all dimensions of function and HRQoL. Compared with conventional medical management alone, patients also receiving spinal cord stimulation (SCS) reported superior pain relief, function, and HRQoL at six months on overall and most sub-component scores. The majority of these improvements with SCS were sustained at 24 months. Nonetheless, 36-40% of patients experienced ongoing marked disability (standing, lifting) and HRQoL problems (pain/discomfort).Conclusions:Longer-term patient management and research must focus on these refractory FBSS patients with persisting poor function and HRQoL outcomes.