Repeatable battery for the assessment of neuropsychological status as a screening test in schizophrenia, II: convergent/discriminant validity and diagnostic group comparisons.

Repeatable battery for the assessment of neuropsychological status as a screening test in schizophrenia, II: convergent/discriminant validity and diagnostic group comparisons.
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DOI:
10.1176/ajp.156.12.1951
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发表时间:
1999-12
期刊:
The American journal of psychiatry
影响因子:
--
通讯作者:
M. Hobart;R. Goldberg;J. Bartko;J. Gold
M. Hobart;R. Goldberg;J. Bartko;J. Gold
中科院分区:
其他
文献类型:
--
作者:
M. Hobart;R. Goldberg;J. Bartko;J. Gold

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在这期杂志的一篇配套文章中,作者提出的数据表明,用于评估神经心理状态的可重复电池(RBANS)对精神分裂症中观察到的损伤类型敏感,与智力和记忆的标准测量高度相关,并且与来自三级护理研究中心的一组精神分裂症患者的就业状况有关。本研究的目的是:1)确定RBANS的收敛效度的证据是否可以在从公共精神卫生系统抽取的诊断异质性样本中复制,2)检查RBANS与广泛的神经心理电池的关系,3)比较精神分裂症患者和双相情感障碍患者在神经心理电池和RBANS上的表现。方法对150名来自一项大型职业康复研究的患者进行了RBANS和标准神经心理学成套测验,包括WAIS-III和韦氏记忆量表(第三版)。结果RBANS总分与WAIS-III和WMS-III变量的相关性在研究组间高度相似。RBANS与综合Z得分高度相关,该综合Z得分来自IQ、记忆、语言、运动、注意力和执行功能的22个标准测量。神经心理电池的主成分分析导致了六个因素的解决方案:RBANS相关性最高的一般能力因素,并与运动性能,警惕性和执行功能的措施有限的相关性。精神分裂症患者表现出更大的赤字比双相情感障碍患者的神经心理电池和RBANS。结论:这些数据表明,RBANS是一个有用的筛选工具,用于评估精神病人群的认知功能障碍的严重程度。
OBJECTIVE In a companion article in this issue of the Journal, the authors presented data suggesting that the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) is sensitive to the types of impairments observed in schizophrenia, correlates highly with standard measures of intelligence and memory, and is related to employment status in a group of patients with schizophrenia drawn from a tertiary care research center. The objectives of the current study were 1) to determine if evidence of the convergent validity of the RBANS could be replicated in a diagnostically heterogeneous sample drawn from a public mental health system, 2) to examine the relationship of the RBANS to a broad neuropsychological battery, and 3) to compare the performance of patients with schizophrenia and patients with bipolar disorder on a neuropsychological battery and the RBANS. METHOD The RBANS and a standard neuropsychological battery, including the WAIS-III and Wechsler Memory Scale, 3rd ed. (WMS-III), were given to 150 patients drawn from a larger study of vocational rehabilitation. RESULTS Correlations of RBANS total scores with WAIS-III and WMS-III variables were highly similar across study groups. The RBANS correlated highly with a composite z score derived from 22 standard measures of IQ, memory, language, motor, attention, and executive function. Principal component analyses of the neuropsychological battery resulted in a six-factor solution: the RBANS correlated most highly with a general ability factor and had limited correlations with measures of motor performance, vigilance, and executive function. Patients with schizophrenia demonstrated greater deficits on the neuropsychological battery and the RBANS than patients with bipolar disorder. CONCLUSIONS These data suggest that the RBANS is a useful screening instrument for assessing the severity of cognitive impairment in psychiatric populations.