Progressive enlargement of scattered photocoagulation scars in diabetic retinopathy
Progressive enlargement of scattered photocoagulation scars in diabetic retinopathy
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DOI：
10.1097/00006982-200408000-00002
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发表时间：
2004-08-01
影响因子：
3.3
通讯作者：
Kishi, S
中科院分区：
文献类型：
--
作者：
Maeshima, K;Utsugi-Sutoh, N;Kishi, S
目的：阐明激光疤痕的演变以及可能影响激光诱导脉络膜视网膜萎缩进展的因素。方法：作者对 19 只患有糖尿病视网膜病变的眼睛进行全视网膜光凝术时形成的 191 个激光疤痕区域进行了量化，并计算了激光疤痕的扩张率。他们还分析了影响扩张的因素，包括位置、激光波长和后续周期。随访时间36～122个月（平均62个月）。结果：大多数（89.5%）激光疤痕逐渐增大。后极的年平均扩张率为 12.7%，中周的年平均扩张率为 7.0%。治疗后4年以上（晚期）的年扩张率（16.5%）高于治疗4年内（早期）的年扩张率（8.8%）。氩激光治疗后扩张率极小（1.2%），而590nm波长激光治疗后扩张率为11.7%，610nm波长激光治疗后扩张率为15.8%。 结论：激光光凝会导致激光疤痕长期持续扩张。激光疤痕在后极扩大得更多。较长波长的激光会导致更大面积的脉络膜视网膜萎缩。
Purpose: To clarify the evolution of laser scars and factors that possibly affect progression of laser-induced chorioretinal atrophy.Methods: The authors quantified 191 areas of laser scarring from panretinal photocoagulation in 19 eyes with diabetic retinopathy and calculated the expansion rate of the laser scars. They also analyzed factors affecting expansion, including location, laser wavelength, and follow-up period. The follow-up period ranged from 36 to 122 months (mean, 62 months).Results: Most (89.5%) laser scars gradually increased in size. The mean annual expansion rates were 12.7% in the posterior pole and 7.0% in the midperiphery. The annual expansion rate (16.5%) more than 4 years (late period) after treatment was higher than that (8.8%) within 4 years of treatment (early period). The expansion rate was minimal (1.2%) after argon laser treatment, whereas it was 11.7% after treatment with a 590-nm wavelength laser and 15.8% after treatment with a 610-nm wavelength laser.Conclusion: Laser photocoagulation causes relentless expansion of laser scars over a long period. Laser scars enlarged more in the posterior pole. Lasers of a longer wavelength contributed to larger areas of chorioretinal atrophy.