BMI and Cause-Specific Hospital Admissions and Costs: The UK Biobank Cohort Study
BMI and Cause-Specific Hospital Admissions and Costs: The UK Biobank Cohort Study
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DOI：
10.1002/oby.22812
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发表时间：
2020-05-21
期刊：
影响因子：
6.9
通讯作者：
Kent, Seamus
中科院分区：
文献类型：
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作者：
O'Halloran, Richard;Mihaylova, Borislava;Kent, Seamus
目的评估BMI对男性和女性特定病因住院率和费用的影响尚不清楚，本研究的目的是解决这一问题。方法对纳入英国生物银行（UK Biobank）的451320名年龄在40岁或以上的男性和女性进行了平均6年的随访，本研究估计了总体和按诊断类别（使用国际疾病分类，第十版章节）与BMI相关的住院年率和费用（按2016年英国价格计算）。结果在从不吸烟的人群中，2 kg/m(2)较高的BMI（高于20 kg/m(2)）与男性入院率增加6.2% （99% CI: 5.3%至7.2%）和年费用增加8.6% （99% CI: 7.3%至10.0%）相关，女性入院率增加5.7% （99% CI: 4.9%至6.6%）和年费用增加8.4% （99% CI: 7.5%至9.3%）相关。较高的BMI与许多类型的健康状况的较高入院率和费用相关，特别是男性和女性的内分泌、皮肤和肌肉骨骼疾病以及男性的循环系统疾病。结论：在各种健康状况下，超过健康体重的BMI与男性和女性较高的年住院率和较高的费用密切相关。
Objective To estimate the effect of BMI on cause-specific hospital admissions and costs in men and women is not well understood, and this study's aim is to address this.Methods For 451,320 men and women aged 40 years or older recruited into the UK Biobank, followed up for 6 years on average, this study estimated annual rates and costs (at 2016 UK prices) of hospital admissions, overall and by diagnostic category (using International Classification of Diseases, Tenth Revision chapters), in relation to BMI.Results Among those who were never smokers, a 2-kg/m(2) higher BMI (above 20 kg/m(2)) was associated with a 6.2% (99% CI: 5.3% to 7.2%) higher admission rate and an 8.6% (99% CI: 7.3% to 10.0%) higher annual cost in men and with a 5.7% (99% CI: 4.9% to 6.6%) higher admission rate and an 8.4% (99% CI: 7.5% to 9.3%) higher annual cost in women. Higher BMI was associated with higher admission rates and costs for many types of health conditions, particularly for endocrine, skin, and musculoskeletal disorders in both men and women and for circulatory diseases in men.Conclusions BMI beyond healthy weight is strongly associated with higher annual rates of hospital admission and higher costs in both men and women across a wide range of health conditions.