Temporal trends in area socioeconomic disparities in breast-cancer incidence and mortality, 1988-2005.

Temporal trends in area socioeconomic disparities in breast-cancer incidence and mortality, 1988-2005.
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DOI:
10.1007/s10549-009-0729-y
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发表时间:
2010-07
影响因子:
3.8
通讯作者:
Jeffe, Donna B.
Jeffe, Donna B.
中科院分区:
医学2区
文献类型:
--
作者:
Schootman, Mario;Lian, Min;Deshpande, Anjali D.;Baker, Elizabeth A.;Pruitt, Sandi L.;Aft, Rebecca;Jeffe, Donna B.

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由于《健康人2010》的总体目标是消除健康差距,我们使用1988-2005年基于人口的乳腺癌数据,确定了五个乳腺癌指标(原位、I期、淋巴结阳性、局部晚期乳腺癌发病率和乳腺癌死亡率)的社会经济差距的时间趋势。使用1988-2005年来自200个县的40岁及以上妇女的监测,流行病学和最终结果计划的数据,我们研究了五个乳腺癌指标在县社会经济贫困四分位数中的时间差异趋势。使用估计的年度百分比变化总结了州一级的趋势。使用贝叶斯分层时空方法对观察到的县发病率进行平滑处理,以计算绝对和相对差异(使用绝对和相对集中指数)及其随时间的变化。自1988年以来,观察到每个贫困四分位数的原位乳腺癌发病率大幅增加。绝对和相对差距都随着时间的推移而增加,这表明各县贫困程度的差距越来越大。其他四个乳腺癌指标的绝对和相对集中指数接近于零,表明1988-2005年期间,县贫困的四个四分位数之间没有差异。根据贫困程度,以县为目标增加乳腺癌筛查的努力可能不会有好处。
Since an overarching goal of Healthy People 2010 was to eliminate health disparities, we determined temporal trends in socioeconomic disparities in five breast-cancer indicators (in situ, stage I, lymph-node positive, and locally advanced breast-cancer incidence, and breast-cancer mortality) by county socioeconomic deprivation using 1988–2005 population-based breast-cancer data. Using 1988–2005 data from women aged 40 and older from 200 counties in the Surveillance, Epidemiology, and End Results program, we examined trends in temporal disparities in the five breast-cancer indicators across quartiles of county socioeconomic deprivation. County-level trends were summarized using the estimated annual percentage change. Observed county rates were smoothed using Bayesian hierarchical spatiotemporal methods to calculate measures of absolute and relative disparity (using absolute and relative concentration indices) and their changes over time. Large increases in in situ breast cancer rates since 1988 were observed for each of the deprivation quartiles. Absolute and relative disparity both increased over time, suggesting increasing disparities across levels of county deprivation. Absolute and relative concentration indices were near zero for the other four breast-cancer indicators, suggesting no disparities among the four quartiles of county deprivation during 1988–2005. Efforts to target counties aimed at increasing breast-cancer screening based on their level of deprivation will not likely be beneficial.
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