Early adiposity rebound: review of papers linking this to subsequent obesity in children and adults
Early adiposity rebound: review of papers linking this to subsequent obesity in children and adults
复制标题
DOI：
10.1097/01.mco.0000168391.60884.93
复制
发表时间：
2005-11-01
影响因子：
3.1
通讯作者：
Williams, SM
中科院分区：
文献类型：
--
作者：
Taylor, RW;Grant, AM;Williams, SM
综述的目的提高我们对导致幼儿肥胖的因素的了解，应该会增加我们管理日益严重的肥胖问题的能力。因此，将肥胖反弹的时间与后期肥胖联系起来的研究进行了综述。许多国家最近的研究结果证实，早期肥胖反弹会增加年轻人患高血压和肥胖的风险。对于那些早期(<；5岁)与晚期(>；7岁)反弹的人来说，这种影响的程度可能是巨大的(18-21岁时为3个体重指数单位)。早期反弹也与成年后的糖耐量受损和糖尿病有关。因为肥胖反弹是通过连续测量体重指数来确定的，所以在这段时间内发生的身体成分的实际变化被掩盖了。最近的数据表明，肥胖反弹期间体重指数的变化是由于体重沉积高于平均水平，而不是身高增长速度放缓。此外，体重增加是由于脂肪的快速沉积而不是瘦组织，早期反弹的人增加脂肪质量的速度几乎是晚期反弹的三倍。总结未来的工作需要找出早期肥胖反弹的原因。由于在肥胖反弹期间，高体力活动和低不活动与较低的体脂有关，因此应该进行研究，看看增加运动是否可以减缓脂肪增加，推迟肥胖反弹的开始，并降低成人肥胖率。
Purpose of review Improving our understanding of factors driving fat gain in young children should increase our ability to manage the rising problem of obesity. Accordingly, studies associating timing of adiposity rebound with later obesity are reviewed.Recent findings Investigations in many countries have confirmed that early adiposity rebound increases risk of high blood pressure and obesity in young adults. The magnitude of the effect can be substantial (> 3 body mass index units at 18 - 21 years) for those undergoing early (< 5 years of age) compared with late (> 7 years of age) rebound. Early rebound is also associated with impaired glucose tolerance and diabetes in adulthood. Because adiposity rebound is determined using serial measurements of body mass index, the actual changes in body composition occurring during this time are obscured. Recent data show that changing body mass index during adiposity rebound is due to higher than average deposition of weight rather than slowing of the rate of height gain. Moreover, this increased weight gain occurs because of rapid deposition of fat rather than lean tissue, with early rebounders gaining fat mass at almost three times the rate of late rebounders.Summary Future work is needed to identify reasons for early adiposity rebound. Because high physical activity and low inactivity are associated with lower body fat during the period of adiposity rebound, studies should be undertaken to see whether stepping up activity can slow fat gain, delay the onset of adiposity rebound and lower adult obesity.